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Thermo Scientific Chemicals
Disuccinimidyl glutarate, 97%
CAS: 79642-50-5 | C13H14N2O8 | 326.26 g/mol
化学物質識別子
CAS79642-50-5
IUPAC Namebis(2,5-dioxopyrrolidin-1-yl) pentanedioate
Molecular FormulaC13H14N2O8
InChI KeyLNQHREYHFRFJAU-UHFFFAOYSA-N
SMILESO=C(CCCC(=O)ON1C(=O)CCC1=O)ON1C(=O)CCC1=O
さらに表示
仕様
スペックシート
スペックシートAppearance (Color)White to cream
FormCrystals or crystalline powder or powder
Assay from Suppliers CofA≥96.0% (TLC)
Identification (FTIR)Conforms
Melting Point130-136°C
さらに表示
Disuccinimidyl glutarate is used as a membrane-soluble, amine-reactive N-hydroxysuccinamide ester-based homobifunctional crosslinking reagent. It is a homobifunctionla cross-linking reagent, for ex. isolation of the insulin receptor.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Disuccinimidyl glutarate is used as a membrane-soluble, amine-reactive N-hydroxysuccinamide ester-based homobifunctional crosslinking reagent. It is a homobifunctionla cross-linking reagent, for ex. isolation of the insulin receptor.
Solubility
Soluble in dimethylsulfoxide and dimethylformamide. Partially soluble in water.
Notes
Moisture sensitive. Store in a cool place. Incompatible with strong oxidizing agents.
Disuccinimidyl glutarate is used as a membrane-soluble, amine-reactive N-hydroxysuccinamide ester-based homobifunctional crosslinking reagent. It is a homobifunctionla cross-linking reagent, for ex. isolation of the insulin receptor.
Solubility
Soluble in dimethylsulfoxide and dimethylformamide. Partially soluble in water.
Notes
Moisture sensitive. Store in a cool place. Incompatible with strong oxidizing agents.
RUO – Research Use Only
General References:
- Morioka, T.; Loik, N. D.; Hipolito, C. J.; Goto, Y.; Suga, H. Selection-based discovery of macrocyclic peptides for the next generation therapeutics. Curr. Opin. Chem. Biol. 2015, 26, 34-41.
- Smaldone, G.; Diana, D.; Pollegioni, L.; Di Gaetano, S.; Fattorusso, R.; Pedone, E. Insight into conformational modification of alpha-synuclein in the presence of neuronal whole cells and of their isolated membranes. FEBS Lett. 2015, 589 (7), 798-804.