Search
元素の検索
構造の検索
Thermo Scientific Chemicals
1-Methyl-1,2,3,4-tetrahydroisoquinoline, 95%
CAS: 4965-09-7 | C9H8NO6 | 226.17 g/mol
化学物質識別子
CAS4965-09-7
IUPAC Name1-methyl-1,2,3,4-tetrahydroisoquinoline
Molecular FormulaC10H13N
InChI KeyQPILYVQSKNWRDD-UHFFFAOYNA-N
SMILESCC1NCCC2=CC=CC=C12
さらに表示
仕様
スペックシート
スペックシートAssay (GC)>94.0%
1-Methyl-1,2,3,4-tetrahydroisoquinoline (1MeTIQ) is an endogenous antidepressant and parkinsonism-preventing substance that demonstrates neuroprotectiveactivity. Following systemic administration in rats, 1-Methyl-1,2,3,4-tetrahydroisoquinoline produces antidepressant-like effect similar to the effect of imipramine. 1MeTIQ is a reversible short-acting moderate inhibitor of MAO A/B. Also known as 1,2,3,4-Tetrahydro-1-methylisoquinoline, 1MeTIQ. It is an important raw material and intermediate for revaprazan and pharmaceutical.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Solubility
Slightly soluble in water.
Notes
Store in freezer at(-20°C). Keep container tightly closed. Store away from oxidizing agent.
Slightly soluble in water.
Notes
Store in freezer at(-20°C). Keep container tightly closed. Store away from oxidizing agent.
RUO – Research Use Only
General References:
- Yoshikazu Tasaki; Yukiko Makino; Shigeru Ohta; and Masaaki Hirobe. 1-Methyl- 1,2,3,4-Tetrahydroisoquinoline, Decreasing in 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Treated Mouse, Prevents Parkinsonism-Like Behavior Abnormalities. Journal of Neurochemistry. >199157(6), 1940-1943,.
- Takahiro Yamakawa; Shigeru Ohta. Isolation of 1-Methyl-1,2,3,4-Tetrahydroisoquinoline-Synthesizing Enzyme from Rat Brain: A Possible Parkinson's Disease-Preventing Enzyme. Biochemical and Biophysical Research Communications. 1997 236 (3), 676-681,.