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Thermo Scientific Chemicals
N-Boc-1,2,5,6-tetrahydropyridine-4-boronic acid pinacol ester, 95%
CAS: 286961-14-6 | C16H28BNO4 | 309.21 g/mol
化学物質識別子
CAS286961-14-6
IUPAC Nametert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2,3,6-tetrahydropyridine-1-carboxylate
Molecular FormulaC16H28BNO4
InChI KeyVVDCRJGWILREQH-UHFFFAOYSA-N
SMILESCC(C)(C)OC(=O)N1CCC(=CC1)B1OC(C)(C)C(C)(C)O1
さらに表示
仕様
スペックシート
スペックシートAssay (HPLC)>94.0%
Reagent used for suzuki-Miyaura cross-coupling using palladium phosphine catalyst, palladium-catalyzed ligand-controlled regioselective Suzuki coupling, wrenchnolol derivative optimized for gene activation in cells. Also used in Preparation of several enzymatic inhibitors and receptor ligands, orally active anaplastic lymphoma kinase inhibitors and oxazolecarboxamides as diacylglycerol acyltransferase-1 inhibitors for treatment of obesity and diabetes.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Reagent used for suzuki-Miyaura cross-coupling using palladium phosphine catalyst, palladium-catalyzed ligand-controlled regioselective Suzuki coupling, wrenchnolol derivative optimized for gene activation in cells. Also used in Preparation of several enzymatic inhibitors and receptor ligands, orally active anaplastic lymphoma kinase inhibitors and oxazolecarboxamides as diacylglycerol acyltransferase-1 inhibitors for treatment of obesity and diabetes.
Solubility
Soluble in most organic solvents. Insoluble in water.
Notes
Store in cool, dry place in tightly closed container. With adequate ventilation. Store away from oxidizing agent.
Reagent used for suzuki-Miyaura cross-coupling using palladium phosphine catalyst, palladium-catalyzed ligand-controlled regioselective Suzuki coupling, wrenchnolol derivative optimized for gene activation in cells. Also used in Preparation of several enzymatic inhibitors and receptor ligands, orally active anaplastic lymphoma kinase inhibitors and oxazolecarboxamides as diacylglycerol acyltransferase-1 inhibitors for treatment of obesity and diabetes.
Solubility
Soluble in most organic solvents. Insoluble in water.
Notes
Store in cool, dry place in tightly closed container. With adequate ventilation. Store away from oxidizing agent.
RUO – Research Use Only
General References:
- Tang, Q; Gianatassio, R. Synthesis of 1,5-disubstituted tetrazoles via Suzuki-Miyaura cross-coupling of 5-chloro-1-phenyltetrazole. Tetrahedron Lett.2010513473-3476.
- Neil A Strotman; Harry R Chobanian; Jiafang He; Yan Guo; Peter G Dormer; Christina M Jones; Janelle E Steves. Catalyst-controlled regioselective Suzuki couplings at both positions of dihaloimidazoles, dihalooxazoles, and dihalothiazoles. Journal of Organic Chemistry.201075(5), 1733-1739.