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Thermo Scientific Chemicals
Loratadine, 98+%
A nonsedating-type histamine H1-receptor antagonist | CAS: 79794-75-5 | C22H23ClN2O2 | 382.888 g/mol
化学物質識別子
CAS79794-75-5
IUPAC Nameethyl 4-{13-chloro-4-azatricyclo[9.4.0.0³,⁸]pentadeca-1(15),3,5,7,11,13-hexaen-2-ylidene}piperidine-1-carboxylate
Molecular FormulaC22H23ClN2O2
InChI KeyJCCNYMKQOSZNPW-UHFFFAOYSA-N
SMILESCCOC(=O)N1CCC(CC1)=C1C2=CC=C(Cl)C=C2CCC2=CC=CN=C12
さらに表示
スペックシートLoratadine, is used as a peripheral histamine H1 receptor agonist. It is also used as an orally active antiallergic agent. It is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals and Dyestuff.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Loratadine, is used as a peripheral histamine H1 receptor agonist. It is also used as an orally active antiallergic agent. It is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals and Dyestuff.
Solubility
It is soluble in DMSO (50 mg/ml), ethanol (77 mg/ml at 25°C), water (<1mg/mL at 25°C), chloroform, and methanol.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2 - 8°C. Keep away fom strong oxidizing agents.
Loratadine, is used as a peripheral histamine H1 receptor agonist. It is also used as an orally active antiallergic agent. It is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals and Dyestuff.
Solubility
It is soluble in DMSO (50 mg/ml), ethanol (77 mg/ml at 25°C), water (<1mg/mL at 25°C), chloroform, and methanol.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2 - 8°C. Keep away fom strong oxidizing agents.
RUO – Research Use Only
General References:
- Barnett et al. Evaluation of the CNS properties of SCH 29851, a potential non-sedating antihistamine. Agents Actions. 1984, 14,(5-6), 590-7.
- Kreutner et al. Antiallergic activity of loratidine, a non-sedating antihistamine. Allergy. 1987, 42,(1), 57-63.