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化学物質識別子
CAS58-55-9
IUPAC Name1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione
Molecular FormulaC7H8N4O2
InChI KeyZFXYFBGIUFBOJW-UHFFFAOYSA-N
SMILESCN1C2=C(NC=N2)C(=O)N(C)C1=O
さらに表示
仕様
スペックシート
スペックシートAppearance (Color)White to off-white
FormPowder
Assay (HPLC)97.0% min.
Loss on Drying0.50% max.
Theophylline has been used to study its effects on rat gene expression in the ubiquitin-proteasome pathway that regulates spermatogenesis and epididymal sperm quality. Theophylline has also been used as an internal standard for the measurement of plasma paracetamol levels in humans.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Theophylline has been used to study its effects on rat gene expression in the ubiquitin-proteasome pathway that regulates spermatogenesis and epididymal sperm quality. Theophylline has also been used as an internal standard for the measurement of plasma paracetamol levels in humans.
Solubility
Soluble in ethanol (moderately), DMSO, alkali hydroxides, ammonia, dilute hyrochloric acid, nitric acid, dilute aqueous acid, and dilute aqueous base. Insoluble in water.
Notes
Store in cool. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.
Theophylline has been used to study its effects on rat gene expression in the ubiquitin-proteasome pathway that regulates spermatogenesis and epididymal sperm quality. Theophylline has also been used as an internal standard for the measurement of plasma paracetamol levels in humans.
Solubility
Soluble in ethanol (moderately), DMSO, alkali hydroxides, ammonia, dilute hyrochloric acid, nitric acid, dilute aqueous acid, and dilute aqueous base. Insoluble in water.
Notes
Store in cool. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.
RUO – Research Use Only
General References:
- Mark W Tengowski; Dongyan Feng; Miriam Sutovsky; Peter Sutovsky. Differential expression of genes encoding constitutive and inducible 20S proteasomal core subunits in the testis and epididymis of theophylline- or 1,3-dinitrobenzene-exposed rats. Biology of Reproduction, 2007, 76(1), 149-163.
- F J Sevilla-Tirado et. al.Bioavailability of two new formulations of paracetamol, compared with three marketed formulations, in healthy volunteers.. Methods and Findings in Experimental and Clinical Pharmacology, 2003,25,(7), 531-535.