Hyaluronic acid, bovine vitreous humor

Name: Hyaluronic acid, bovine vitreous humor
SKU: J60566.MF

Hyaluronic acid from bovine vitreous humor, CAS # 9004-61-9, is a naturally derived glycosaminoglycan that shows an angiogenic activity that promotes wound healing processes. | CAS: 9004-61-9 | C28H44N2O23 | 776.651 g/mol

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10 mg

50 mg

100 mg

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製品番号（カタログ番号） J60566.MF

または、製品番号J60566-MF

価格（JPY）

数量:

50 mg

一括またはカスタム形式をリクエストする

化学物質識別子

CAS9004-61-9

IUPAC Namesodium (2S,3S,4R,5R,6R)-3-{[(2S,3R,4R,5S,6R)-4-{[(2R,3R,4S,5S,6S)-6-carboxy-3,4,5-trihydroxyoxan-2-yl]oxy}-3-acetamido-5-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-6-{[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy}-4,5-dihydroxyoxane-2-carboxylic acid

Molecular FormulaC28H44N2NaO23

InChI KeyYWIVKILSMZOHHF-QJZPQSOGSA-N

SMILES[Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@@H]1O[C@@H]([C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O[C@@H]3O[C@@H]([C@@H](O)[C@H](O)[C@H]3O)C(O)=O)[C@H]2NC(C)=O)[C@H](O)[C@H]1O)C(O)=O

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仕様

スペックシート

Appearance (Color)White to cream

CommentSubstrate suitability: Satisfactory for hyaluronidase assay

FormPowder

Hyaluronic acid is a naturally derived, non - immunogenic, non - adhesive glycosaminoglycan that plays a prominent role in various wound - healing processes, as it as it is naturally angiogenic when degraded to small fragments. Hyaluronic acid promotes early inflammation which is critical for initiating wound healing, but then moderates later stages of the process, allowing matrix stabilization and reduction of long term inflammation.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

Hyaluronic acid, derived from bovine vitreous humor, is a naturally derived, non-immunogenic, non-adhesive glycosaminoglycan that shows an angiogenic activity promoting wound-healing processes when degraded to small fragments

Application

It is considered a mucopolysaccharide composed of repeating dimeric units of glucuronic acid and N-acetyl glucosamine, which forms the core of complex proteoglycan aggregates found in the extracellular matrix
It has been used to study the activation of the MAPK/ERK pathway following infection of macrophages with Leishmania amazonensis

RUO – Research Use Only

General References:

Yuushi Okumura. Serase-1B, a new splice variant of polyserase-1/TMPRSS9, activates urokinase-type plasminogen activator and the proteolytic activation is negatively regulated by glycosaminoglycans. Biochemical Journal. 2006, 400, (4), 551-555.