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Thermo Scientific Chemicals
Vincristine sulfate, 97+%
An anti-tumor alkaloid used in cancer research | CAS: 2068-78-2 | C46H58N4O14S | 923.044 g/mol
化学物質識別子
CAS2068-78-2
IUPAC Namemethyl (1R,9R,10S,11R,12R,19R)-11-(acetyloxy)-12-ethyl-4-[(13S,15S,17S)-17-ethyl-17-hydroxy-13-(methoxycarbonyl)-1,11-diazatetracyclo[13.3.1.0⁴,¹².0⁵,¹⁰]nonadeca-4(12),5,7,9-tetraen-13-yl]-8-formyl-10-hydroxy-5-methoxy-8,16-diazapentacyclo[10.6.1.0¹,⁹.0²,⁷.0¹⁶,¹⁹]nonadeca-2(7),3,5,13-tetraene-10-carboxylate; sulfuric acid
Molecular FormulaC46H58N4O14S
InChI KeyAQTQHPDCURKLKT-JKDPCDLQSA-N
SMILESOS(O)(=O)=O.CC[C@]1(O)C[C@H]2CN(C1)CCC1=C(NC3=CC=CC=C13)[C@@](C2)(C(=O)OC)C1=CC2=C(C=C1OC)N(C=O)[C@@H]1[C@]22CCN3CC=C[C@](CC)([C@@H]23)[C@@H](OC(C)=O)[C@]1(O)C(=O)OC
さらに表示
仕様
スペックシート
スペックシートAssay (HPLC)≥97.0%
Vincristine sulfate, is used as an anticancer agent, microtubule disrupter, Induces apoptosis in human lymphoma cells. Other applications include as a cell cycle arresting, apoptotic inducing alkaloid.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Solubility
Soluble in DMSO at 60mg/ml. Soluble in water at 25mg/ml with warming. Very poorly soluble in ethanol
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20°C. Keep away fom strong oxidizing agents, heavy metal salts.
Soluble in DMSO at 60mg/ml. Soluble in water at 25mg/ml with warming. Very poorly soluble in ethanol
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20°C. Keep away fom strong oxidizing agents, heavy metal salts.
RUO – Research Use Only
General References:
- Jordan et al. Comparison of the effects of vinblastine, vincristine, vindesine, and vinepidine on microtubule dynamics and cell proliferation in vitro. Cancer Res. 1985, 45 ,(6), 2741-7.
- Takano et al. Apoptosis induced by microtubule disrupting drugs in cultured human lymphoma cells. Inhibitory effects of phorbol ester and zinc sulphate. Pathol.Res.Pract. 1993, 189 ,(2), 197-203.