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Thermo Scientific Chemicals
Felodipine
A dihydropyridine calcium channel blocker | CAS: 72509-76-3 | C18H19Cl2NO4 | 384.253 g/mol
化学物質識別子
CAS72509-76-3
IUPAC Name3-ethyl 5-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
Molecular FormulaC18H19Cl2NO4
InChI KeyRZTAMFZIAATZDJ-UHFFFAOYNA-N
SMILESCCOC(=O)C1=C(C)NC(C)=C(C1C1=CC=CC(Cl)=C1Cl)C(=O)OC
さらに表示
仕様
スペックシート
スペックシートPurity≥95.0%
Mass SpecConforms
FormPowder or crystals or crystalline powder
Appearance (Color)Yellow to yellow-green
Felodipine is used as a dihydropyridine calcium channel blocker. It displays high vascular selectivity; lowers arterial blood pressure without altering cardiac contractility. Antihypertensive.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Felodipine is used as a dihydropyridine calcium channel blocker. It displays high vascular selectivity; lowers arterial blood pressure without altering cardiac contractility. Antihypertensive.
Solubility
Soluble in DMSO. Insoluble in water
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Keep away from strong oxidizing agents.
Felodipine is used as a dihydropyridine calcium channel blocker. It displays high vascular selectivity; lowers arterial blood pressure without altering cardiac contractility. Antihypertensive.
Solubility
Soluble in DMSO. Insoluble in water
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Keep away from strong oxidizing agents.
RUO – Research Use Only
General References:
- Ljung. Vascular selectivity of felodipine: experimental pharmacology. J.Cardiovasc.Pharmacol. 1990, 15,(4), S11-6.
- Furukawa et al. Selectivities of dihydropyridine derivatives in blocking Ca2+ channel subtypes expressed inXenopus oocytes. J.Pharmacol.Exp.Ther. 1999, 291,(2), 464-73.