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Thermo Scientific Chemicals
Guanosine-5'-triphosphate disodium salt
CAS: 56001-37-7 | C10H14N5Na2O14P3 | 567.14 g/mol
化学物質識別子
CAS56001-37-7
IUPAC Namedisodium phosphono ({[(2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphonato}oxy)phosphonate
Molecular FormulaC10H14N5Na2O14P3
InChI KeyFIZIYLKEXVIRHJ-KHRSEZDTNA-L
SMILES[Na+].[Na+].NC1=NC2=C(N=CN2[C@@H]2O[C@H](COP([O-])(=O)OP([O-])(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)C(=O)N1
さらに表示
仕様
スペックシート
スペックシートAssay (HPLC)90.0% min.
Loss on Drying15.0% max.
Appearance (Color)White to off-white
FormPowder
Guanosine 5?-triphosphate (GTP), a purine trinucleotide, is a substrate for RNA polymerases and a wide range of GTPase including G-protein coupled receptor (GPCR) GTPases and cell signaling and cycling associated guanine nucleotide exhange factors (GEF). Guanosine 5?-Triphosphate, Disodium Salt is a phosphoryl donor in protein synthesis and in signal transduction.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Guanosine 5′-triphosphate (GTP), a purine trinucleotide, is a substrate for RNA polymerases and a wide range of GTPase including G-protein coupled receptor (GPCR) GTPases and cell signaling and cycling associated guanine nucleotide exhange factors (GEF). Guanosine 5′-Triphosphate, Disodium Salt is a phosphoryl donor in protein synthesis and in signal transduction.
Solubility
Soluble in water.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2 - 8°C. Keep away from strong oxidizing agents.
Guanosine 5′-triphosphate (GTP), a purine trinucleotide, is a substrate for RNA polymerases and a wide range of GTPase including G-protein coupled receptor (GPCR) GTPases and cell signaling and cycling associated guanine nucleotide exhange factors (GEF). Guanosine 5′-Triphosphate, Disodium Salt is a phosphoryl donor in protein synthesis and in signal transduction.
Solubility
Soluble in water.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2 - 8°C. Keep away from strong oxidizing agents.
RUO – Research Use Only
General References:
- ES Simon.; S Grabowski. Convenient Syntheses of Cytidine 5'-triphosphate, Guanosine 5'-triphosphate, and Uridine 5'-triphosphate and their Use in the Preparation of UDP-Glucose, UDP. J. Org. Chem. 1990, 55, (6), 1834-1841.
- KE Achyuthan.; CS Greenberg. Identification of a guanosine triphosphate-binding site on guinea pig liver transglutaminase. Role of GTP and calcium ions in modulating activity. J.Biol.Chem. 1987, 262, 1901-1906.