Search
元素の検索
構造の検索
Thermo Scientific Chemicals
Cholic acid sodium salt, Thermo Scientific Chemicals
Biochemical solubilizing agent
化学物質識別子
CAS206986-87-0
IUPAC Namesodium (4R)-4-[(1R,3aS,3bR,4R,5aS,7R,9aS,9bS,11S,11aR)-4,7,11-trihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanoate
Molecular FormulaC24H39NaO5
InChI KeyNRHMKIHPTBHXPF-TUJRSCDTSA-M
SMILES[Na+].[H][C@@]12CC[C@H]([C@H](C)CCC([O-])=O)[C@@]1(C)[C@@H](O)C[C@@]1([H])[C@@]2([H])[C@H](O)C[C@]2([H])C[C@H](O)CC[C@]12C
さらに表示
仕様
スペックシート
スペックシートAppearance (Color)White to pale cream
Assay from Suppliers CofA≥98.0%
Loss on Drying≤5.0%
FormPowder
Cholic acid sodium salt is a bio-surfactant which can be used as a reducing reagent in aqueous solution. It is also used as a non-denaturing detergent used for extraction of membrane proteins. Sodium cholate hydrate has been used in a study to assess the effect of phospholipid formulation and surfactants on the dermal delivery of hydrophilic drugs from elastic liposomes. It has also been used in a study to investigate the elastic deformable vesicles, transfersomes, for transdermal drug delivery.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Cholic acid sodium salt is a bio-surfactant which can be used as a reducing reagent in aqueous solution. It is also used as a non-denaturing detergent used for extraction of membrane proteins. Sodium cholate hydrate has been used in a study to assess the effect of phospholipid formulation and surfactants on the dermal delivery of hydrophilic drugs from elastic liposomes. It has also been used in a study to investigate the elastic deformable vesicles, transfersomes, for transdermal drug delivery.
Solubility
It is soluble in water.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Keep away from strong oxidizing agents.
Cholic acid sodium salt is a bio-surfactant which can be used as a reducing reagent in aqueous solution. It is also used as a non-denaturing detergent used for extraction of membrane proteins. Sodium cholate hydrate has been used in a study to assess the effect of phospholipid formulation and surfactants on the dermal delivery of hydrophilic drugs from elastic liposomes. It has also been used in a study to investigate the elastic deformable vesicles, transfersomes, for transdermal drug delivery.
Solubility
It is soluble in water.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Keep away from strong oxidizing agents.
RUO – Research Use Only
General References:
- Kevin B Ita et. al. Dermal delivery of selected hydrophilic drugs from elastic liposomes: effect of phospholipid formulation and surfactants. Journal of Pharmacy and Pharmacology. 2007, 59, (9), 1215-1222.
- Yan Qiao et. al. Controllable synthesis of water-soluble gold nanoparticles and their applications in electrocatalysis and surface-enhanced Raman scattering. Langmuir. 2011, 27, (17), 11090-11097.