Erythromycin, Cell Culture Grade

Name: Erythromycin, Cell Culture Grade
SKU: J62279.14

Erythromycin (E-Mycin or erythrocin), CAS # 114-07-8, is a broad-spectrum antibiotic. | CAS: 114-07-8 | C37H67NO13 | 733.94 g/mol

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数量:

10 g

25 g

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製品番号（カタログ番号） J62279.14

または、製品番号J62279-14

価格（JPY）

数量:

25 g

一括またはカスタム形式をリクエストする

化学物質識別子

CAS114-07-8

IUPAC Name(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecane-2,10-dione

Molecular FormulaC37H67NO13

InChI KeyULGZDMOVFRHVEP-RWJQBGPGSA-N

SMILESCC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O

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仕様

スペックシート

Assay from Supplier's CofA93.0-100.5% (sum of erythromycin A, B and C, dry weight basis)

Residue on ignition≤0.2%

Optical Rotation-74.5° ±3.5°

FormCrystals or powder or crystalline powder

Residual water≤6.5%

さらに表示

Erythromycin, is used as a macrolide antibiotic protein synthesis inhibitor. It is widely used in cell culture applications. Depending upon the strain of bacteria, erythromycin has been used between 50 and 200 mg/L to control bacterial growth. Erythromycin resistance can be induced in bacteria.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

Erythromycin is a macrolide antibiotic that works by binding the 50S ribosomal subunit and inhibiting polypeptide formation
Erythromycin was isolated from Saccharopolyspora erythraea

Applications

Erythromycin can be used to disrupt the growth of gram-positive and gram-negative bacteria
Erythromycin has been shown to have motor effects in the gastrointestinal system and can be used for laboratory research on migrating motor complex activity

RUO – Research Use Only

General References:

Dreno, B.; Martin, R.; Moyal, D.; Henley, J.B.; Khammari, A.; Seité, S. Skin microbiome and acne vulgaris: Staphylococcus, a new actor in acne. Exp Dermatol. 2017, 26(9), 798-803.
Wu, F.; Tokach, M.D.; DeRouchey, J.M.; Dritz, S.S.; Woodworth, J.C.; Goodband, R.D.; Chitakasempornkul, K.; Bello, N.M.; Capps, K.; Remfry, S.; Scott, H.M.; Nagaraja, T.G.; Apley, M.D.; Amachawadi, R.G. Effects of Tylosin Administration Routes on the Prevalence of Antimicrobial Resistance Among Fecal Enterococci of Finishing Swine. Foodborne Pathog Dis. 2019, 16(5), 309-316.