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Thermo Scientific Chemicals
Bumetanide, 98+%
Inhibitor of the sodium-potassium-chloride cotransporter | CAS: 28395-03-1 | C17H20N2O5S | 364.416 g/mol
仕様
CAS28395-03-1
ChEBICHEBI:3213
化学物質名または材質Bumetanide
色White
EINECS番号249-004-6
さらに表示
Bumetanide has been observed to block the depolarization of GABA in cortical development studies. It is been used as a specific inhibitor of Na+-K+-2Cl- cotransporter NKCC1
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Bumetanide has been observed to block the depolarization of GABA in cortical development studies. It is been used as a specific inhibitor of Na+-K+-2Cl- cotransporter NKCC1
Solubility
Soluble in ethanol (10 mg/ml), DMSO (25 mg/ml), acetone, benzene, methanol, propylene glycol, and water (<1mg/mL).
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Keep away from acids.
Bumetanide has been observed to block the depolarization of GABA in cortical development studies. It is been used as a specific inhibitor of Na+-K+-2Cl- cotransporter NKCC1
Solubility
Soluble in ethanol (10 mg/ml), DMSO (25 mg/ml), acetone, benzene, methanol, propylene glycol, and water (<1mg/mL).
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Keep away from acids.
RUO – Research Use Only
General References:
- Star, R.A., et al. Luminal disequilibrium pH and ammonia transport in outer medullary collecting duct. Am. J. Physiol. 1987, 252( 6 Pt 2), F1148-F1157.
- O'Grady, S.M., et al. Characteristics and functions of Na-K-Cl cotransport in epithelial tissues. Am. J. Physiol. 1987, 253( 2 Pt 1), C177-C192.