Search Thermo Fisher Scientific
元素の検索
構造の検索Thermo Scientific Chemicals
Fluocinolone acetonide, Thermo Scientific Chemicals
製品番号（カタログ番号）： J63996.03
1 g, Each
化学物質識別子
CAS
67-73-2
IUPAC Name
(1S,2S,4R,8S,9S,11S,12R,13S,19S)-12,19-difluoro-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.0²,⁹.0⁴,⁸.0¹³,¹⁸]icosa-14,17-dien-16-one
Molecular Formula
C24H30F2O6
InChI Key
FEBLZLNTKCEFIT-VSXGLTOVSA-N
SMILES
CC1(C)O[C@@H]2C[C@H]3[C@@H]4C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@@]4(F)[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO
仕様
スペックシートAppearance (Color)
White to off-white
Assay (unspecified)
≥98.0%
Infrared spectrum
Conforms
Form
Powder
概要
Fluocinolone acetonide is primarily used in dermatology to reduce skin inflammation and relieve itching. It acts as an inhibitor of tumor cells and it can regulate lipid metabolism by modulating gene expression. It can also inhibit the expression of VEGF (vascular endothelial growth factor) in the retinal pigment epithelial cell line due to its high glucocorticoid receptor affinity. Furthermore, it can inhibit TNF-α angiogenesis.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Fluocinolone acetonide is primarily used in dermatology to reduce skin inflammation and relieve itching. It acts as an inhibitor of tumor cells and it can regulate lipid metabolism by modulating gene expression. It can also inhibit the expression of VEGF (vascular endothelial growth factor) in the retinal pigment epithelial cell line due to its high glucocorticoid receptor affinity. Furthermore, it can inhibit TNF-α angiogenesis.
Solubility
Soluble in water (partly), DMSO, alcohol, chloroform and methanol.
Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents.
Fluocinolone acetonide is primarily used in dermatology to reduce skin inflammation and relieve itching. It acts as an inhibitor of tumor cells and it can regulate lipid metabolism by modulating gene expression. It can also inhibit the expression of VEGF (vascular endothelial growth factor) in the retinal pigment epithelial cell line due to its high glucocorticoid receptor affinity. Furthermore, it can inhibit TNF-α angiogenesis.
Solubility
Soluble in water (partly), DMSO, alcohol, chloroform and methanol.
Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents.
RUO – Research Use Only
図
ドキュメントおよびダウンロード
証明書
ロット番号または部分ロット番号で検索
よくあるご質問（FAQ）
引用および参考文献
Search citations by name, author, journal title or abstract text