Doxycycline hydrochloride, 20 mg/ml in distilled water, sterile-filtered
Doxycycline hydrochloride, 20 mg/ml in distilled water, sterile-filtered
Doxycycline hydrochloride, 20 mg/ml in distilled water, sterile-filtered
Thermo Scientific Chemicals

Doxycycline hydrochloride, 20 mg/ml in distilled water, sterile-filtered

Doxycycline hydrochloride, CAS # 10592-13-9, is the hydrochloride salt form of doxycycline that shows antibacterial and antimalarial activities. | CAS: 10592-13-9 | C22H25ClN2O8 | 480.90 g/mol
製品番号(カタログ番号) J67043.AD
または、製品番号J67043-AD
価格(JPY)
-
数量:
50 mL
一括またはカスタム形式をリクエストする
化学物質識別子
CAS10592-13-9
FormLiquid
Appearance (Color)Clear pale yellow
CommentComponent is dissolved in UV treated 18.2 megohm-cm ± 1, endotoxin tested water (Endotoxin content: ≥ 0.1EU/ml). The solution is filtered through 0.22 micron filter.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Suitable for battery materials development.

General Description

• Doxycycline hydrochloride is a compound that shows antibacterial and antimicrobial activities against several species, including Pseudomonas aeruginosa, Plasmodium falciparum, and Escherichia coli. It is also a bacteriostatic

• It can block the binding of aminoacyl-tRNA to the mRNA-ribosome complex, thereby inhibiting protein synthesis

Application

• It is used to eliminate Borrelia burgdorferi and Anaplasma phagocytophilum in rodent reservoirs and eliminate Ixodes scapularis ticks

• Doxycycline hydrochloride is also considered to be a broad-spectrum inhibitor used to inhibit matrix metalloproteinases (MMP), such as type 1 collagenase, in wound healing and tissue remodeling studies. Due to this activity, it can inhibit angiogenesis and reduce lung metastases

RUO – Research Use Only

General References:

  1. Z Qiang.; C Adams. Potentiometric determination of acid dissociation constants (pK a) for human and veterinary antibiotics. Water research. 2004, 38, (12), 2874-2890.
  2. JB Bogardus.; RK Blackwood. Solubility of doxycycline in aqueous solution. Journal of Pharmaceutical Sciences. 1979, 68, (2), 188-194.