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Thermo Scientific™
1-(Heptafluorobutyryl)imidazole, 97%
CAS: 32477-35-3 | C7H3F7N2O | 264.103 g/mol
化学物質識別子
CAS32477-35-3
IUPAC Name2,2,3,3,4,4,4-heptafluoro-1-(1H-imidazol-1-yl)butan-1-one
Molecular FormulaC7H3F7N2O
InChI KeyMSYHGYDAVLDKCE-UHFFFAOYSA-N
SMILESFC(F)(F)C(F)(F)C(F)(F)C(=O)N1C=CN=C1
さらに表示
仕様
スペックシート
スペックシートAppearance (Color)Clear to slightly turbid colorless to yellow or pale orange to pink
FormLiquid
Assay (GC)≥96.0%
Refractive Index1.3825-1.3875 @20°C
1-(Heptafluorobutyryl)imidazole is used in gas chromatography for the determination of various pharmaceutical compounds like retronecine in biological matrixes. It acts as a reagent for derivatize amine-groups. It plays an essential role to reduce GC column degradation due to its non-acidic property. It is an acylating agent, which converts thermally unstable compounds to its more volatile derivative and then made suitable for GC analysis.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
1-(Heptafluorobutyryl)imidazole is used in gas chromatography for the determination of various pharmaceutical compounds like retronecine in biological matrixes. It acts as a reagent for derivatize amine-groups. It plays an essential role to reduce GC column degradation due to its non-acidic property. It is an acylating agent, which converts thermally unstable compounds to its more volatile derivative and then made suitable for GC analysis.
Solubility
Miscible with chloroform and methanol.
Notes
Hygroscopic and air sensitive. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents.
1-(Heptafluorobutyryl)imidazole is used in gas chromatography for the determination of various pharmaceutical compounds like retronecine in biological matrixes. It acts as a reagent for derivatize amine-groups. It plays an essential role to reduce GC column degradation due to its non-acidic property. It is an acylating agent, which converts thermally unstable compounds to its more volatile derivative and then made suitable for GC analysis.
Solubility
Miscible with chloroform and methanol.
Notes
Hygroscopic and air sensitive. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents.
RUO – Research Use Only
General References:
- GC derivatization reagent for amino and hydroxyl groups: Anal. Lett., 1, 311 (1968); 2, 81 (1969); compare Heptafluorobutyric anhydride, A10744.
- Zhou, H.; Jin, Q.; Wang, X.; Xu, X. Direct measurement of 3-chloropropane-1,2-diol fatty acid esters in oils and fats by HPLC method. Food Control 2014, 36 (1), 111-118.
- Nie, Z.; Zhang, Y.; Chen, J.; Lin, Y.; Wu, B.; Dong, Y.; Feng, J.; Liu, Q.; Xie, J. Monitoring urinary metabolites resulting from sulfur mustard exposure in rabbits, using highly sensitive isotope-dilution gas chromatography-mass spectrometry Anal. Bioanal. Chem. 2014, 406 (21), 5203-5212.