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Thermo Scientific Chemicals
Tropine, 98%
CAS: 120-29-6 | C8H15NO | 141.214 g/mol
化学物質識別子
CAS120-29-6
IUPAC Name8-methyl-8-azabicyclo[3.2.1]octan-3-ol
Molecular FormulaC8H15NO
InChI KeyCYHOMWAPJJPNMW-UHFFFAOYNA-N
SMILESCN1C2CCC1CC(O)C2
さらに表示
仕様
スペックシート
スペックシートAppearance (Color)White to pale cream
FormCrystalline powder
Assay (GC)> 97.5%
Water Content (Karl Fischer Titration)< 3.0%
Assay (Non-aqueous acid-base Titration)>97.5 to <102.5% (dry wt. basis)
Tropine as an oxidative product of Tropane, used to synthesize alkaloid derivatives. Benzatropine and etybenzatropine are derivatives of tropine. It is also a building block of atropine, an anticholinergic drug prototypical of the muscarinic antagonist class.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Tropine as an oxidative product of Tropane, used to synthesize alkaloid derivatives. Benzatropine and etybenzatropine are derivatives of tropine. It is also a building block of atropine, an anticholinergic drug prototypical of the muscarinic antagonist class.
Solubility
Soluble in water. (100 g/L) at 20°C.
Notes
Hygroscopic. Store at 4°C. Incomaptible with Strong acids and oxidizing agents.
Tropine as an oxidative product of Tropane, used to synthesize alkaloid derivatives. Benzatropine and etybenzatropine are derivatives of tropine. It is also a building block of atropine, an anticholinergic drug prototypical of the muscarinic antagonist class.
Solubility
Soluble in water. (100 g/L) at 20°C.
Notes
Hygroscopic. Store at 4°C. Incomaptible with Strong acids and oxidizing agents.
RUO – Research Use Only
General References:
- Muriel E. Farquharson and R. G. Johnston. Antagonism Of The Effects Of Tremorine By Tropine Derivatives.British Journal of Pharmacology and Chemotherapy.1959, 14 559-566.
- Edward. Leete. The Stereospecific Incorporation of Ornithine into the Tropine Moiety of Hyoscyamine.J. Am. Chem. Soc.1962, 84 (1), 55-57.