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Thermo Scientific Chemicals
4-Cyclohexylaniline, 97%
CAS: 6373-50-8 | C16H12Cl2N4OS | 379.26 g/mol
化学物質識別子
CAS6373-50-8
IUPAC Name1-(2,4-dichlorophenyl)-3-[5-(4-methylphenyl)-1,3,4-thiadiazol-2-yl]urea
Molecular FormulaC16H12Cl2N4OS
InChI KeyYDTTUXLKBBQRHA-UHFFFAOYSA-N
SMILESCC1=CC=C(C=C1)C1=NN=C(NC(=O)NC2=CC=C(Cl)C=C2Cl)S1
さらに表示
仕様
スペックシート
スペックシートAppearance (Color)White to yellow to orange to cream to pale brown
Assay (GC)≥96.0%
FormCrystals or powder or crystalline powder
Melting Point (clear melt)49.0-58.0?C
4-Cyclohexylaniline is used as a starting material for the preparation of 1-cyclohexyl-4-nitroso-benzene. It is used as a reactant in nucleophilic acylation to form N-(4-cyclohexylphenyl)acetamide by reacting with acetyl halides. It is also involved in the synthesis of N-(4-cyclohexylphenyl)-2-morpholino-acetamide by reaction with 2-morpholinoacetyl fluoride. Further, it reacts with 4-bromo-4-oxo-butanoic acid to get 4-[(4-cyclohexylphenyl)amino]-4-oxo-butanoic acid.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
4-Cyclohexylaniline is used as a starting material for the preparation of 1-cyclohexyl-4-nitroso-benzene. It is used as a reactant in nucleophilic acylation to form N-(4-cyclohexylphenyl)acetamide by reacting with acetyl halides. It is also involved in the synthesis of N-(4-cyclohexylphenyl)-2-morpholino-acetamide by reaction with 2-morpholinoacetyl fluoride. Further, it reacts with 4-bromo-4-oxo-butanoic acid to get 4-[(4-cyclohexylphenyl)amino]-4-oxo-butanoic acid.
Solubility
Insoluble in water.
Notes
Incompatible with strong oxidizing agents.
4-Cyclohexylaniline is used as a starting material for the preparation of 1-cyclohexyl-4-nitroso-benzene. It is used as a reactant in nucleophilic acylation to form N-(4-cyclohexylphenyl)acetamide by reacting with acetyl halides. It is also involved in the synthesis of N-(4-cyclohexylphenyl)-2-morpholino-acetamide by reaction with 2-morpholinoacetyl fluoride. Further, it reacts with 4-bromo-4-oxo-butanoic acid to get 4-[(4-cyclohexylphenyl)amino]-4-oxo-butanoic acid.
Solubility
Insoluble in water.
Notes
Incompatible with strong oxidizing agents.
RUO – Research Use Only
General References:
- Mou, J.; Park, A.; Cai, Y.; Yuan, J.; Yuan, C. Structure-activity relationship study of E6 as a novel necroptosis inducer. Bioorg. Med. Chem. Lett. 2015, 25 (15), 3057-3061.
- Wei, W.; Wen, J.; Yang, D.; Sun, X.; You, J.; Suo, Y.; Wang, H. Iron-catalyzed three-component tandem process: a novel and convenient synthetic route to quinoline-2,4-dicarboxylates from arylamines, glyoxylic esters, and alpha-ketoesters. Tetrahedron 2013, 69 (50), 10747-10751.