3-Methylindole is often used as a component of commercial fragrances and perfumes.It helps fluorescent guanosine analogue, which in a dimethoxytrityl, phosphoramidite protected form, can be site-specifically inserted into oligonucleotides through a 3?5?phosphodiester linkage using an automated DNA synthesizer
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
3-Methylindole is often used as a component of commercial fragrances and perfumes.It helps fluorescent guanosine analogue, which in a dimethoxytrityl, phosphoramidite protected form, can be site-specifically inserted into oligonucleotides through a 3?5?phosphodiester linkage using an automated DNA synthesizer
Solubility
Soluble in water, Ether, Alcohols, Benzene, Acetone, Chloroform.
Notes
Light Sensitive. Store in dark away from oxidizing agents. Incompatible with light, strong acids, acid ahydrides, acid chlorides.
RUO – Research Use Only
General References:
- E. Hardin Strickland; Joseph Horwitz; Carolyn Billups. Near-ultraviolet absorption bands of tryptopan. Studies using indole and 3-methylindole as models.Biochemistry.1970, 9 (25), 4914-4921.
- J Thornton-Manning; M L Appleton; F J Gonzalez and G S Yost. Metabolism of 3-methylindole by vaccinia-expressed P450 enzymes: correlation of 3-methyleneindolenine formation and protein-binding.JPET.1996, 276 (1), 21-29.