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Thermo Scientific Chemicals
4-Chloro-1-butanol, tech. 85%
CAS: 928-51-8 | C4H9ClO | 108.57 g/mol
化学物質識別子
CAS928-51-8
仕様
スペックシート
スペックシートAppearance (Color)Clear to slightly hazy colorless to yellow or pale pink
Assay (GC)≥80.0%
Refractive Index1.4510-1.4630 @ 20°C
Free acid (titration)≤6.0% as HCl
FormLiquid
4-Chloro-1-butanol is employed as an internal standard in the analysis of genotoxic impurities in active pharmaceutical ingredients by GC-MS technique.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
4-Chloro-1-butanol is employed as an internal standard in the analysis of genotoxic impurities in active pharmaceutical ingredients by GC-MS technique.
Solubility
Soluble in methanol, chloroform, and dimethyl sufoxide.
Notes
Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. Incompatible with oxidizing agents.
4-Chloro-1-butanol is employed as an internal standard in the analysis of genotoxic impurities in active pharmaceutical ingredients by GC-MS technique.
Solubility
Soluble in methanol, chloroform, and dimethyl sufoxide.
Notes
Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. Incompatible with oxidizing agents.
RUO – Research Use Only
General References:
- Otto Bastiansen.; Liv Fernholt.; Kenneth Hedberg.; Ragnhild Seip. Structure and conformations of 4-chloro-1-butanol: electron-diffraction evidence for internal hydrogen bonding. J. Am. Chem. Soc. 1985, 107 (26), 7836-7841.
- Koki Harigaya.; Hiroyuki Yamada.; Koji Yaku.; Hiroyuki Nishi.; Jun Haginaka. Development and validation of a sensitive GC-MS method for the determination of alkylating agent, 4-chloro-1-butanol, in active pharmaceutical ingredients. Journal of Molecular Biology. 1997, 113 (1), 237-251.