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Thermo Scientific Chemicals
5-Methylindole, 99%
CAS: 614-96-0 | C9H9N | 131.178 g/mol
化学物質識別子
CAS614-96-0
IUPAC Name5-methyl-1H-indole
Molecular FormulaC9H9N
InChI KeyYPKBCLZFIYBSHK-UHFFFAOYSA-N
SMILESCC1=CC=C2NC=CC2=C1
さらに表示
仕様
スペックシート
スペックシートAppearance (Color)White to cream to pale yellow
Identification (FTIR)Conforms
FormCrystals or powder or crystalline powder
Melting Point (clear melt)56.0-62.0?C
Assay (GC)≥98.5%
5-Methylindole is used as reactant for preparation of pharmaceutically active 2-oxo-1-pyrrolidine analogues, potential anticancer immunomodulators, IL2-inducible T-cell kinase (ITK) inhibitors and CRTh2 antagonists.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
5-Methylindole is used as reactant for preparation of pharmaceutically active 2-oxo-1-pyrrolidine analogues, potential anticancer immunomodulators, IL2-inducible T-cell kinase (ITK) inhibitors and CRTh2 antagonists.
Solubility
Insoluble in water.
Notes
Light sensitive. Incompatible with oxidizing agents and heat.
5-Methylindole is used as reactant for preparation of pharmaceutically active 2-oxo-1-pyrrolidine analogues, potential anticancer immunomodulators, IL2-inducible T-cell kinase (ITK) inhibitors and CRTh2 antagonists.
Solubility
Insoluble in water.
Notes
Light sensitive. Incompatible with oxidizing agents and heat.
RUO – Research Use Only
General References:
- Ran Jiang; Hai-Yan Xu; Xiao-Ping Xu; Xue-Qiang Chu; Shun-Jun Ji. Direct alkylation of indoles and amines by tert-enamides: facile access to pharmaceutically active 2-oxo-1-pyrrolidine analogues. Organic & Biomolecular Chemistry. 2011, 9,(16), 5659-5669.
- Eduard Dolusic; Pierre Larrieu; Laurence Moineaux; Vincent Stroobant; Luc Pilotte; Didier Colau; Lionel Pochet; Benoit Van den Eynde; Bernard Masereel; Johan Wouters; Raphael Frederick. Tryptophan 2,3-dioxygenase (TDO) inhibitors. 3-(2-(pyridyl)ethenyl)indoles as potential anticancer immunomodulators. Journal of medicinal and pharmaceutical chemistry. 2011, 54,(15), 5320-5334.