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Thermo Scientific Chemicals
2,2-Di-n-propylacetamide, 97%
CAS: 2430-27-5 | C8H17NO | 143.23 g/mol
化学物質識別子
CAS2430-27-5
仕様
スペックシート
スペックシートAppearance (Color)White
Assay (GC)≥96.0%
FormCrystals or powder or crystalline powder or fused solid
Melting Point (clear melt)120.0-130.0?C
It is employed as an antiepileptic drug. It is hydrolyzed quickly to VPA in vivo, but has intrinsic anticonvulsant activity. Also a reactant used in the synthesis of mutual prodrugs containing bio-cleavable and drug releasable disulfide linkers.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Solubility
Soluble in chloroform, dimethyl sulfoxide and methanol. Insoluble in water.
Notes
Store in cool. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.
Soluble in chloroform, dimethyl sulfoxide and methanol. Insoluble in water.
Notes
Store in cool. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.
RUO – Research Use Only
General References:
- Ilan Winkler; Simcha Blotnik; Jakob Shimshoni; Boris Yagen; Marshall Devor; Meir Bialer. Efficacy of antiepileptic isomers of valproic acid and valpromide in a rat model of neuropathic pain. British Journal of Pharmacology. 2005, 146 (2), 198-208.
- Galit Shaltiel et. al. Valproate decreases inositol biosynthesis. Biological Psychiatry. 2004, 56(11), 868-874.