Imidazole-2-carboxaldehyde, 97%
Imidazole-2-carboxaldehyde, 97%
Imidazole-2-carboxaldehyde, 97%
Thermo Scientific Chemicals

Imidazole-2-carboxaldehyde, 97%

CAS: 10111-08-7 | C4H4N2O | 96.09 g/mol
製品番号(カタログ番号) L13883.14
価格(JPY)
-
数量:
25 g
一括またはカスタム形式をリクエストする
化学物質識別子
CAS10111-08-7
IUPAC Name1H-imidazole-2-carbaldehyde
Molecular FormulaC4H4N2O
InChI KeyXYHKNCXZYYTLRG-UHFFFAOYSA-N
SMILESO=CC1=NC=CN1
さらに表示
Appearance (Color)White to dark cream to cream to yellow to orange to brown
Assay (HPLC)≥96.0%
FormCrystals or powder or crystalline powder or lumps
Imidazole-2-carboxaldehyde is a novel protein tyrosine phosphatase 1B (PTP1B) inhibitor with an important application to treat type-2 diabetes. It is used in the preparation of tridentate Schiff-base carboxylate-containing ligands by undergoing condensation reaction with amino acids beta-alanine and 2-aminobenzoic acid. It is also involved in the study of the imidazole-directed allylation of aldimines.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Imidazole-2-carboxaldehyde is a novel protein tyrosine phosphatase 1B (PTP1B) inhibitor with an important application to treat type-2 diabetes. It is used in the preparation of tridentate Schiff-base carboxylate-containing ligands by undergoing condensation reaction with amino acids beta-alanine and 2-aminobenzoic acid. It is also involved in the study of the imidazole-directed allylation of aldimines.

Solubility
Soluble in water.

Notes
Air sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents.
RUO – Research Use Only

General References:

  1. Joseyphus, R. S.; Shiju, C.; Joseph, J.; Dhanaraj, C. J.; Arish, D. Synthesis and characterization of metal complexes of Schiff base ligand derived from imidazole-2-carboxaldehyde and 4-aminoantipyrine. Spectrochim. Acta, Part A 2014, 133, 149-155.
  2. Tinel, L.; Dumas, S.; George, C. A time-resolved study of the multiphase chemistry of excited carbonyls: Imidazole-2-carboxaldehyde and halides. C. R. Chim. 2014, 17 (7), 801-807.