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Thermo Scientific Chemicals
3-Bromo-N,N-dimethylaniline, 97%
CAS: 16518-62-0 | C8H10BrN | 200.08 g/mol
化学物質識別子
CAS16518-62-0
IUPAC Name3-bromo-N,N-dimethylaniline
Molecular FormulaC8H10BrN
InChI KeyUSEXQPWLCGBYNT-UHFFFAOYSA-N
SMILESCN(C)C1=CC=CC(Br)=C1
さらに表示
仕様
スペックシート
スペックシートAppearance (Color)Clear colorless to yellow to orange
FormLiquid
Identification (FTIR)Conforms
Assay (GC)≥96.0%
Refractive Index1.5990-1.6040 @ 20?C
3-Bromo-N,N-dimethylaniline is involved in fluorination using metal fluoride in the presence of 2-(di-1-adamantylphosphino)-3,6-dimethoxy-2',4',6'-tri-i-propyl-1,1'-biphenyl (AdBrettPhos)-based Pd precatalyst, used to prepare 3-fluoro-N,N- dimethylaniline.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
3-Bromo-N,N-dimethylaniline is involved in fluorination using metal fluoride in the presence of 2-(di-1-adamantylphosphino)-3,6-dimethoxy-2′,4′,6′-tri-i-propyl-1,1′-biphenyl (AdBrettPhos)-based Pd precatalyst, used to prepare 3-fluoro-N,N- dimethylaniline.
Solubility
Miscible with chloroform, dichloromethane and methanol.
Notes
Light sensitive. Store in cool place. Incompatible with strong oxidizing agents and strong acids.
3-Bromo-N,N-dimethylaniline is involved in fluorination using metal fluoride in the presence of 2-(di-1-adamantylphosphino)-3,6-dimethoxy-2′,4′,6′-tri-i-propyl-1,1′-biphenyl (AdBrettPhos)-based Pd precatalyst, used to prepare 3-fluoro-N,N- dimethylaniline.
Solubility
Miscible with chloroform, dichloromethane and methanol.
Notes
Light sensitive. Store in cool place. Incompatible with strong oxidizing agents and strong acids.
RUO – Research Use Only
General References:
- Sursvakova, V. V.; Burmakina, G. V.; Rubaylo, A. I. Palladium-Catalyzed Oxidative Carbonylation of Aromatic C-H Bonds of N-Alkylanilines with CO and Alcohols for the Synthesis of o-Aminobenzoates. J. Org. Chem. 2015, 80 (2), 1258-1263.
- Ding, Q.; Zhou, X.; Pu, S.; Cao, B. Rhodium-catalyzed ortho-selective C-H halogenation of 2-arylbenzo[d]thiazoles using N-halosuccinimides as halogen sources. Tetrahedron 2015, 71 (16), 2376-2381.