2-Bromo-4-fluorobenzoic acid, 98%
2-Bromo-4-fluorobenzoic acid, 98%
2-Bromo-4-fluorobenzoic acid, 98%
2-Bromo-4-fluorobenzoic acid, 98%
Thermo Scientific Chemicals

2-Bromo-4-fluorobenzoic acid, 98%

CAS: 1006-41-3 | C7H4BrFO2 | 219.009 g/mol
製品番号(カタログ番号) L19321.14
または、製品番号L19321-14
価格(JPY)
-
見積もりを依頼する
数量:
25 g
一括またはカスタム形式をリクエストする
化学物質識別子
CAS1006-41-3
IUPAC Name2-bromo-4-fluorobenzoate
Molecular FormulaC7H3BrFO2
InChI KeyRRKPMLZRLKTDQV-UHFFFAOYSA-M
SMILES[O-]C(=O)C1=CC=C(F)C=C1Br
さらに表示
Appearance (Color)White to cream
FormCrystals or powder or crystalline powder
Assay (Aqueous acid-base Titration)≥97.5 to ≤102.5%
Melting Point (clear melt)169.0-176.0?C
Assay (Silylated GC)≥97.5%
2-Bromo-4-fluorobenzoic acid is used in the synthesis of 3-fluoro-8-(methylthio)dibenzo[b,f]thiepin-10(11H)-one, 2-fluoro-8-(methylthio)dibenzo[b,f]thiepin-10(11H)-one, 2-((2-carboxy-5-fluorophenyl)amino)-3-methoxybenzoic acid and 2-bromo-4-fluorobenzamide. It is also used in the preparation of boron-containing anti-fungal agents, in the treatment of onychomycosis.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
2-Bromo-4-fluorobenzoic acid is used in the synthesis of 3-fluoro-8-(methylthio)dibenzo[b,f]thiepin-10(11H)-one, 2-fluoro-8-(methylthio)dibenzo[b,f]thiepin-10(11H)-one, 2-((2-carboxy-5-fluorophenyl)amino)-3-methoxybenzoic acid and 2-bromo-4-fluorobenzamide. It is also used in the preparation of boron-containing anti-fungal agents, in the treatment of onychomycosis.

Solubility
Soluble in water and methanol.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible with oxidizing agents.
RUO – Research Use Only

General References:

  1. Lauren R Donaldson.; Stephen Wallace.; David Haigh.; E Elizabeth Patton.; Alison N Hulme. Rapid synthesis and zebrafish evaluation of a phenanthridine-based small molecule library. Organic & Biomolecular Chemistry. 2011, 9 (7), 2233-2239.
  2. Christian Wolf.; Shuanglong Liu.; Xuefeng Mei.; Adam T August.; Michael D Casimir. Regioselective copper-catalyzed amination of bromobenzoic acids using aliphatic and aromatic amines. Journal of Organic Chemistry. 2006, 71 (8), 3270-3273.