LDS 751

Citations & References (42)

Invitrogen™

LDS 751

LDS 751は、dsDNA上で約543 nmのピーク励起を持つ細胞透過性核酸染色剤で、長い最大発光波長（約712 nm）を持つことから、マルチカラー分析に特に有用です。LDS詳細を見る

製品番号（カタログ番号）	数量
L7595	10 mg

製品番号（カタログ番号） L7595

価格（JPY）

51,300

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10 mg

LDS 751は、dsDNA上で約543 nmのピーク励起を持つ細胞透過性核酸染色剤で、長い最大発光波長（約712 nm）を持つことから、マルチカラー分析に特に有用です。LDS 751をdsDNAに結合すると、蛍光強度が最大で約20倍に増強されます。

研究用にのみ使用できます。診断用には使用いただけません。

検出法蛍光

染色剤タイプLDS 751

励起波長域543⁄712

使用対象 (装置)フローサイトメーター

数量10 mg

出荷条件室温

製品タイプ核酸染色

SubCellular Localization核、核酸, Nucleus

Unit SizeEach

組成および保存条件

LDS 751（10 mg）のバイアル1本入りです。室温で保存し、光から保護します。

よくあるご質問（FAQ）

LDS 751 (Cat.# L7595) を用いる際のプロトコルありませんか?

Flow cytometry and FISH to measure the average length of telomeres (flow FISH).Baerlocher GM, Vulto I, de Jong G, Lansdorp PMNat. Protoc. 2006; (1):5 2365-2376http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&dopt=AbstractPlus&list_uids=17406480*有核血球細胞を染色後、FCM解析 (詳細なプロトコル)Staining of cellular mitochondria with LDS-751.Snyder DS, Small PLJ. Immunol. Methods 2001; (257):1-2 35-40http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&dopt=AbstractPlus&list_uids=11687236*LDS 751でミトコンドリアを染色

引用および参考文献 (42)

引用および参考文献

Abstract

Dyes providing increased sensitivity in flow-cytometric dye-efflux assays for multidrug resistance.

Authors:Frey T, Yue S, Haugland RP

Journal:Cytometry

PubMed ID:7587707

In an effort to improve detection of P-glycoprotein-mediated multidrug resistance (mdr), several dyes were compared to rhodamine 123 (R123) in efflux assays. Two dyes (SY-38 and SY-3150) were found that provided better sensitivity. These dyes were effluxed by a cell line known to be mdr-positive (P388/R84) but not by an ... More

Modulation of platelet-neutrophil interaction with pharmacological inhibition of fibrinogen binding to platelet GPIIb/IIIa receptor.

Authors:Xiao Z, Théroux P, Frojmovic M

Journal:Thromb Haemost

PubMed ID:10064007

'The study investigated how drug inhibition of the GPIIb/IIIa receptor influences the interactions between platelets and leukocytes. These interactions are believed to play an important role in the etiology of the acute coronary syndromes. Thirty patients with unstable angina or non-Q-wave myocardial infarction were studied before the administration of tirofiban ... More

Discriminating between damaged and intact cells in fixed flow cytometric samples.

Authors:Terstappen LW, Shah VO, Conrad MP, Recktenwald D, Loken MR

Journal:Cytometry

PubMed ID:2460298

'A vital, nucleic acid stain (LDS-751) was used to discriminate intact from damaged cells in a flow cytometer even after the samples had been fixed with paraformaldehyde. Three major cell populations with different fluorescence properties with LDS-751 were found in the fixed samples. Cells not staining or only dimly staining ... More

The Q-Prep system: effects on the apparent expression of leucocyte cell surface antigens.

Authors:Macey MG, McCarthy DA, Davies C, Newland AC

Journal:Cytometry

PubMed ID:9149913

'To facilitate the analysis of immunolabelled peripheral blood or bone marrow leucocytes by flow cytometry, a number of reagents are available commercially that lyse erythrocytes and fix leucocytes. This study has investigated the effect on antibody-labelled whole blood of the Q-Prep procedure, in which erythrocytes are lysed with formic acid, ... More

Interaction of LDS-751 and rhodamine 123 with P-glycoprotein: evidence for simultaneous binding of both drugs.

Authors:Lugo MR, Sharom FJ

Journal:Biochemistry

PubMed ID:16229491

'The P-glycoprotein efflux pump, an ABC superfamily member, can export a wide variety of hydrophobic drugs, natural products, and peptides from cells, powered by the energy of ATP hydrolysis. Transport substrates appear to first partition into the membrane and then interact with the protein within the cytoplasmic leaflet. Two drug ... More

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