Medium 154

Citations & References (5)

Gibco™

Medium 154

ヒト表皮ケラチン生成細胞培養用に塩化カルシウム200µMで調製された滅菌液体培地。この基本培地を使用するには、使用前にHKGS（S-001-5）キットまたはHKGSキット（S-001-K）を付加する必要があります。詳細を見る

製品番号（カタログ番号）	数量
M154500	500 mL

製品番号（カタログ番号） M154500

価格（JPY）

16,400

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500 mL

ヒト表皮ケラチン生成細胞培養用に塩化カルシウム200µMで調製された滅菌液体培地。この基本培地を使用するには、使用前にHKGS（S-001-5）キットまたはHKGSキット（S-001-K）を付加する必要があります。

研究用にのみ使用できます。診断用には使用いただけません。

細胞タイプKeratinocyte Cells

無機塩類Calcium

製品ラインCascade Biologics

製品タイプMedium 154

数量500 mL

出荷条件Room Temperature

分類Serum-free

Culture TypeMammalian Cell Culture

形状Liquid

Serum LevelSerum-free

無菌性Sterile-filtered

Sterilization MethodSterile-filtered

添加剤ありPhenol Red

Unit SizeEach

組成および保存条件

Store at 4°C.

引用および参考文献 (5)

引用および参考文献

Abstract

MART-1 is required for the function of the melanosomal matrix protein PMEL17/GP100 and the maturation of melanosomes.

Authors:Hoashi T, Watabe H, Muller J, Yamaguchi Y, Vieira WD, Hearing VJ,

Journal:J Biol Chem

PubMed ID:15695812

More than 125 genes that regulate pigmentation have been identified to date. Of those, MART-1 has been widely studied as a melanoma-specific antigen and as a melanosome-specific marker. Whereas the functions of other melanosomal proteins, such as tyrosinase, tyrosinase-related protein-1, dopachrome tautomerase, and Pmel17, are known, the function of MART-1 ... More

Src family kinase inhibitors block amphiregulin-mediated autocrine ErbB signaling in normal human keratinocytes.

Authors:Kansra S, Stoll SW, Johnson JL, Elder JT,

Journal:Mol Pharmacol

PubMed ID:15615697

c-Src potentiates proliferation, survival, and invasiveness in response to epidermal growth factor (EGF) in human mammary carcinoma cells. Tyrosine (Tyr) 845 of ErbB1 is phosphorylated by Src and has been implicated in control of malignant behavior. Although several lines of evidence also suggest important interactions of ErbB and Src family ... More

Biochemical characterization of S100A2 in human keratinocytes: subcellular localization, dimerization, and oxidative cross-linking.

Authors:Deshpande R, Woods TL, Fu J, Zhang T, Stoll SW, Elder JT,

Journal:J Invest Dermatol

PubMed ID:10951287

S100A2 is a calmodulin-like protein of unknown function, whose transcription is positively regulated in response to ErbB and p53 signaling. Expression of S100A2 is markedly increased in the context of ErbB-driven reactive epidermal hyperplasia, and decreased in the context of hypofunctional p53 mutations in carcinoma cell lines and tumors. This ... More

Interferon-gamma reduces melanosomal antigen expression and recognition of melanoma cells by cytotoxic T cells.

Authors:Le Poole IC, Riker AI, Quevedo ME, Stennett LS, Wang E, Marincola FM, Kast WM, Robinson JK, Nickoloff BJ,

Journal:Am J Pathol

PubMed ID:11839572

In malignant melanoma, tumor-infiltrating lymphocytes are frequently reactive with melanosomal antigens. Achieving complete remissions by peptide therapy is frequently hampered by metastases evading immune recognition. The tumor microenvironment seems to favor reduced expression of target antigens by melanoma cells. Among candidate factors, interferon-gamma (IFN-gamma) (10(2) to 10(3) U/ml) suppressed expression ... More

Genetic analysis of the human papillomavirus type 31 differentiation-dependent late promoter.

Authors:Bodily JM, Meyers C,

Journal:J Virol

PubMed ID:15731225

Human papillomaviruses infect stratifying squamous epithelia, causing benign and malignant lesions. Upon differentiation of the host keratinocyte, the virus undergoes a dramatic increase in both DNA replication and transcription from the late promoter, leading to expression of late genes and virion morphogenesis. In human papillomavirus type 31 (HPV31), the late ... More