NBD Cholesterol (22-(N-(7-Nitrobenz-2-Oxa-1,3-Diazol-4-yl)Amino)-23,24-Bisnor-5-Cholen-3β-Ol)
NBD Cholesterol (22-(<i>N</i>-(7-Nitrobenz-2-Oxa-1,3-Diazol-4-yl)Amino)-23,24-Bisnor-5-Cholen-3&beta;-Ol)
Invitrogen™

NBD Cholesterol (22-(N-(7-Nitrobenz-2-Oxa-1,3-Diazol-4-yl)Amino)-23,24-Bisnor-5-Cholen-3β-Ol)

この蛍光アナログNBDコレステロールは、膜内部に局所化する環境に敏感なプローブで、脂質輸送プロセスや脂質-タンパク質間の相互作用の調査に役立ちます詳細を見る
製品番号(カタログ番号)数量
N114810 mg
製品番号(カタログ番号) N1148
価格(JPY)
56,100
온라인 행사
Ends: 27-Mar-2026
93,500
割引額 37,400 (40%)
Each
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数量:
10 mg
この蛍光アナログNBDコレステロールは、膜内部に局所化する環境に敏感なプローブで、脂質輸送プロセスや脂質-タンパク質間の相互作用の調査に役立ちます。
研究用にのみ使用できます。診断用には使用いただけません。
仕様
化学物質名または材質Cholesterol Analogs
励起/発光469/537 nm
推奨保存方法Store at room temperature and protect from light.
物理的フォームSolid
製品ラインInvitrogen
数量10 mg
Unit SizeEach

引用および参考文献 (64)

引用および参考文献
Abstract
Inactivation of NPC1L1 causes multiple lipid transport defects and protects against diet-induced hypercholesterolemia.
Authors:Davies JP, Scott C, Oishi K, Liapis A, Ioannou YA
Journal:J Biol Chem
PubMed ID:15671032
'NPC1L1, a recently identified relative of Niemann-Pick C1, was characterized to determine its subcellular location and potential function(s). NPC1L1 was highly expressed in HepG2 cells and localized in a subcellular vesicular compartment rich in the small GTPase Rab5. mRNA expression profiling revealed significant differences between mouse and man with highest ... More
High density lipoprotein-mediated cholesterol uptake and targeting to lipid droplets in intact L-cell fibroblasts. A single- and multiphoton fluorescence approach.
Authors:Frolov A, Petrescu A, Atshaves BP, So PT, Gratton E, Serrero G, Schroeder F
Journal:J Biol Chem
PubMed ID:10777574
'Fluorescent sterols, dehydroergosterol and NBD-cholesterol, were used to examine high density lipoprotein-mediated cholesterol uptake and intracellular targeting in L-cell fibroblasts. The uptake, but not esterification or targeting to lipid droplets, of these sterols differed >100-fold, suggesting significant differences in uptake pathways. NBD-cholesterol uptake kinetics and lipoprotein specificity reflected high density ... More
Lipid binding to sterol carrier protein-2 is inhibited by ethanol.
Authors:Avdulov NA, Chochina SV, Igbavboa U, Warden CS, Schroeder F, Wood WG
Journal:Biochim Biophys Acta
PubMed ID:9931423
'Sterol carrier protein-2 (SCP-2) is an intracellular lipid carrier protein that binds cholesterol, phospholipids, fatty acids and other ligands. It has been reported that expression of SCP-2 was increased in brain nerve endings or synaptosomes of chronic ethanol-treated mice and it was shown that cholesterol homeostasis was altered in brain ... More
Formation of membrane domains created during the budding of vesicular stomatitis virus. A model for selective lipid and protein sorting in biological membranes.
Authors:Luan P, Yang L, Glaser M
Journal:Biochemistry
PubMed ID:7543280
'Vesicular stomatitis virus buds from domains of the plasma membrane that have a unique protein and lipid composition. Fluorescence digital imaging microscopy and resonance energy transfer were used to determine how the two viral envelope-associated proteins, the G and the M proteins, could alter the lateral distribution of lipids in ... More
Membrane properties of D-erythro-N-acyl sphingomyelins and their corresponding dihydro species.
Authors:Kuikka M, Ramstedt B, Ohvo-Rekilä H, Tuuf J, Slotte JP
Journal:Biophys J
PubMed ID:11325733
'We have prepared acyl chain-defined D-erythro-sphingomyelins and D-erythro-dihydrosphingomyelins and compared their properties in monolayer and bilayer membranes. Surface pressure/molecular area isotherms of D-erythro-N-16:0-sphingomyelin (16:0-SM) and D-erythro-N-16:0-dihydrosphingomyelin (16:0-DHSM) show very similar packing properties, except that the expanded-to-condensed phase transition (crystallization) occurs at a lower surface pressure for 16:0-DHSM. The measured surface ... More