NP-EGTA (o-Nitrophenyl EGTA, Tetrapotassium Salt, cell impermeant

NP-EGTA (<i>o</i>-Nitrophenyl EGTA, Tetrapotassium Salt, cell impermeant

Citations & References (90)

Invitrogen™

NP-EGTA (o-Nitrophenyl EGTA, Tetrapotassium Salt, cell impermeant

NPケージドEGTA、カリウム塩は、UV照射時にCa2+ に対して高い選択性を示し、そのKdは80 nMから>1 mMまで増加する細胞不透過性の光解離性キレート剤です。NP-EGTA塩は、Ca2+と複合化して、光分解時に光分解時にCa2+放出するケージドカルシウム複合体を生成することができます詳細を見る

製品番号（カタログ番号）	数量
N6802 または、製品番号N-6802	1 mg

製品番号（カタログ番号） N6802

または、製品番号N-6802

価格（JPY）

113,600

お問い合わせください ›

NPケージドEGTA、カリウム塩は、UV照射時にCa²⁺ に対して高い選択性を示し、そのKdは80 nMから>1 mMまで増加する細胞不透過性の光解離性キレート剤です。NP-EGTA塩は、Ca²⁺と複合化して、光分解時に光分解時にCa²⁺放出するケージドカルシウム複合体を生成することができます。

カルシウム、カリウム、pH、膜電位インジケータなどのイオンインジケータの詳細については、こちらを参照してください›

研究用にのみ使用できます。診断用には使用いただけません。

染色剤タイプキレート剤（非蛍光）

数量1 mg

出荷条件室温

製品タイプNP-EGTA

Unit SizeEach

組成および保存条件

フリーザー（-5℃～-30℃）に保存し、遮光してください。

引用および参考文献 (90)

引用および参考文献

Abstract

Spatially organised mitochondrial calcium uptake through a novel pathway in chick neurones.

Authors:Coatesworth W, Bolsover S

Journal:Cell Calcium

PubMed ID:16338004

'A brief depolarisation of chick sensory neurones evokes a calcium increase in mitochondria that peaks 1-2s after the depolarisation event and then decays over tens of seconds. Peripheral mitochondria take up more calcium than do central ones, even when the cytosolic calcium increase is spatially homogeneous. The calcium influx into ... More

Ion selectivities of the Ca(2+) sensors for exocytosis in rat phaeochromocytoma cells.

Authors:Kishimoto T, Liu TT, Ninomiya Y, Takagi H, Yoshioka T, Ellis-Davies GC, Miyashita Y, Kasai H

Journal:J Physiol

PubMed ID:11410622

'1. The ion selectivities of the Ca(2+) sensors for the two components of exocytosis in rat phaeochromocytoma (PC12) cells were examined by measurement of membrane capacitance and amperometry. The cytosolic concentrations of metal ions were increased by photolysis of caged-Ca(2+) compounds and measured with low-affinity indicators benzothiazole coumarin (BTC) or ... More

Early requirement for alpha-SNAP and NSF in the secretory cascade in chromaffin cells.

Authors:Xu T, Ashery U, Burgoyne RD, Neher E

Journal:EMBO J

PubMed ID:10369670

'NSF and alpha-SNAP have been shown to be required for SNARE complex disassembly and exocytosis. However, the exact requirement for NSF and alpha-SNAP in vesicular traffic through the secretory pathway remains controversial. We performed a study on the kinetics of exocytosis from bovine chromaffin cells using high time resolution capacitance ... More

Roles of Ca2+ and crossbridge kinetics in determining the maximum rates of Ca2+ activation and relaxation in rat and guinea pig skinned trabeculae.

Authors:Palmer S, Kentish JC

Journal:Circ Res

PubMed ID:9686757

'We examined the influences of Ca2+ and crossbridge kinetics on the maximum rate of force development during Ca2+ activation of cardiac myofibrils and on the maximum rate of relaxation. Flash photolysis of diazo-2 or nitrophenyl-EGTA was used to produce a sudden decrease or increase, respectively, in [Ca2+] within Triton-skinned trabeculae ... More

Ca2+ entry in CHO cells, after Ca2+ stores depletion, is mediated by arachidonic acid.

Authors:Gailly P

Journal:Cell Calcium

PubMed ID:9883283

'Transfected Chinese hamster ovary cells expressing the rat neurotensin receptor (CHO-NTR cells) were used to study the 'Ca2+ stores depletion-Ca2+ entry' coupling which follows stimulation with neurotensin and liberation of inositol 1,4,5-trisphosphate. This coupling could be dissociated in time: the stores were emptied by stimulation with neurotensin in the absence ... More

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