A phospho specific antibody directed to the ezrin⁄radixin⁄moesin (ERM) peptide that is a substrate for LRRK2 (Leucine-rich repeat kinase 2) and LRRK2 mutants. Mutations in LRRK2 have been found to be related to late-onset Parkinson's disease. For use in combination with the Fluorescein-ERM (LRRKtide) substrate (PV4901) to evaluate inhibitors in medium to high throughput screening applications.
For Research Use Only. Not for use in diagnostic procedures.
仕様
抗原
Serine/threonine kinase
アプリケーション
Kinase Assay
濃度
0.52mg/mL
コンジュゲート
Tb (Terbium)/Lanthanide Chelates
抗原の分子量
150kDa
数量
1 mg
規制状況
RUO, RUO
研究領域
Pharma and Biopharma
一次または二次
Primary
パッケージ
1 Each
形状
Liquid
励起/発光
340⁄490, 520
反応性
Human
出荷条件
Dry Ice
結果
End Point
反応性の略語
Hu
標的遺伝子
Ser/Thr Kinases
製品ライン
LanthaScreen™
組成および保存条件
Terbium-labeled pERM (pLRRKtide) antibody in HEPES buffered saline. Store at -20°C.