SYTO™ 41 Blue Fluorescent Nucleic Acid Stain - 5 mM Solution in DMSO

Citations & References (8)

Invitrogen™

SYTO™ 41 Blue Fluorescent Nucleic Acid Stain - 5 mM Solution in DMSO

細胞透過型SYTO41青色蛍光核酸染色剤は、核酸に結合すると明るい青色の蛍光を示します。生細胞におけるSYTO色素の染色パターンは細胞の種類によって異なる可能性があるため、当社ではSYTO青色蛍光核酸染色サンプラーキット（S-11350）を提供しており、研究者は特定のアプリケーションに最適な色素を見つけることができます。詳細を見る

製品番号（カタログ番号）	数量
S11352	250 μL

製品番号（カタログ番号） S11352

価格（JPY）

44,400

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Ends: 27-Mar-2026

74,100

割引額 29,700 (40%)

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250 μL

研究用にのみ使用できます。診断用には使用いただけません。

概要SYTO™ 41 Blue Fluorescent Nucleic Acid Stain - 5 mM Solution in DMSO

検出法蛍光

染色剤タイプ細胞透過性

発光454 nm

励起波長域430⁄454

使用対象 (装置)蛍光顕微鏡

製品ラインSYTO

数量250 μL

出荷条件室温

容量（メートル法）250 μL

標識タイプFluorescent Dye

製品タイプ核酸染色

SubCellular Localization核酸

Unit SizeEach

組成および保存条件

フリーザー（-5℃～-30℃）に保存し、遮光してください。

よくあるご質問（FAQ）

How do SYTO dyes bind to DNA?

The binding mode of SYTO nucleic acid stains is unknown. However, the behavior of these and related nucleic acid dyes suggests the following binding properties:

1.They appear to contact the solvent (suggested by sensitivity to salt, divalent cations, and in particular, SDS) and thus are likely to have contacts in the grooves.
2.All SYTO dyes appear to show some base selectivity and are thus likely to have minor groove contacts.
3.They can be removed from nucleic acid via ethanol precipitation; this characteristic is not shared by ethidium bromide and other intercalators. Likewise, the dyes are not removed from nucleic acid via butanol or chloroform extraction. These extraction methods do remove ethidium bromide from nucleic acid. 4. SYTO binding is not affected by nonionic detergents.
5. SYTO dyes are not quenched by BrdU, so they do not bind nucleic acids in precisely the same way as Hoechst 33342 and DAPI ((4′,6-diamidino-2-phenylindole).

SYBR Green I has shown little mutagenicity on frameshift indicator strains, indicating that it isn't likely to strongly intercalate.

Find additional tips, troubleshooting help, and resources within our Cell Analysis Support Center.

引用および参考文献 (8)

引用および参考文献

Abstract

Nucleic acid binding agents exert local toxic effects on neurites via a non-nuclear mechanism.

Authors:Pin S, Chen H, Lein PJ, Wang MM

Journal:J Neurochem

PubMed ID:16441515

'The mechanism by which drugs that target nucleic acids cause neurotoxicity is not well described. We characterized the neurotoxicity of Hoechst 33342 (bis-benzimide), a common cell permeable nuclear dye, in primary neuronal cultures. The mechanism of cell death was not apoptotic, as death is rapid, not accompanied by typical nuclear ... More

Imaging collagen in intact viable healthy and atherosclerotic arteries using fluorescently labeled CNA35 and two-photon laser scanning microscopy.

Authors:Megens RT, Oude Egbrink MG, Cleutjens JP, Kuijpers MJ, Schiffers PH, Merkx M, Slaaf DW, van Zandvoort MA,

Journal:Mol Imaging

PubMed ID:17711780

We evaluated CNA35 as a collagen marker in healthy and atherosclerotic arteries of mice after both ex vivo and in vivo administration and as a molecular imaging agent for the detection of atherosclerosis. CNA35 conjugated with fluorescent Oregon Green 488 (CNA35/OG488) was administered ex vivo to mounted viable muscular (uterine), ... More

Two pathways converge at CED-10 to mediate actin rearrangement and corpse removal in C. elegans.

Authors:Kinchen JM, Cabello J, Klingele D, Wong K, Feichtinger R, Schnabel H, Schnabel R, Hengartner MO

Journal:Nature

PubMed ID:15744306

The removal of apoptotic cells is essential for the physiological well being of the organism. In Caenorhabditis elegans, two conserved, partially redundant genetic pathways regulate this process. In the first pathway, the proteins CED-2, CED-5 and CED-12 (mammalian homologues CrkII, Dock180 and ELMO, respectively) function to activate CED-10 (Rac1). In ... More

Two-photon microscopy of vital murine elastic and muscular arteries. Combined structural and functional imaging with subcellular resolution.

Authors:Megens RT, Reitsma S, Schiffers PH, Hilgers RH, De Mey JG, Slaaf DW, oude Egbrink MG, van Zandvoort MA

Journal:J Vasc Res

PubMed ID:17192719

Understanding vascular pathologies requires insight in the structure and function, and, hence, an imaging technique combining subcellular resolution, large penetration depth, and optical sectioning. We evaluated the applicability of two-photon laser-scanning microscopy (TPLSM) in large elastic and small muscular arteries under physiological conditions. Elastic (carotid) and muscular (uterine, mesenteric) arteries ... More

Loss of α-gal during primate evolution enhanced antibody-effector function and resistance to bacterial sepsis.

Authors:

Journal:Cell Host Microbe

PubMed ID:33497603

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