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          System Message

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          LOADING ...
          See other TP53 SIRNA Assays ›
          Gene Symbol:
          TP53
          Gene Name:
          tumor protein p53
          Gene Aliases:
          BCC7, LFS1, P53, TRP53
          Chromosome Location:
          Chr.17: 7668402 - 7687550 on Build GRCh38
          UniGene ID:
          Hs.437460
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID 106141
          Validated

          Purification
          Size
          Availability Inventoried
          Catalog # AM51331
          Price 6,301.00
          Your Price
          Online offer:
          6301.0
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: TP53
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_000546.5 NP_000537.3 11 1673
          NM_001126112.2 NP_001119584.1 11 1670
          NM_001126113.2 NP_001119585.1 12 1733
          NM_001126114.2 NP_001119586.1 12 1806
          NM_001126115.1 NP_001119587.1 7 1353
          NM_001126116.1 NP_001119588.1 8 1486
          NM_001126117.1 NP_001119589.1 8 1413
          NM_001126118.1 NP_001119590.1 10 1790
          NM_001276695.1 NP_001263624.1 12 1733
          NM_001276696.1 NP_001263625.1 12 1806
          NM_001276697.1 NP_001263626.1 7 1353
          NM_001276698.1 NP_001263627.1 8 1486
          NM_001276699.1 NP_001263628.1 8 1413
          NM_001276760.1 NP_001263689.1 11 1673
          NM_001276761.1 NP_001263690.1 11 1670
          GenBank mRNA AB082923.1 - 11 1534
          AF052180.1 - 1 305
          AF307851.1 - 11 1606
          AK223026.1 - 5 766
          AK297462.1 - 12 1538
          AK297927.1 - 12 1583
          BC003596.1 - 11 1591 3544714
          DQ186648.1 - 12 1736
          DQ186649.1 - 12 1663
          DQ186650.1 - 7 1349
          DQ186651.1 - 8 1482
          DQ186652.1 - 8 1409
          DQ191317.1 - 11 1660
          DQ286964.1 - 11 1605
          FJ207420.1 - 11 1606
          JN214348.1 - 10 1516
          JN900492.1 - 10 1779
          X01405.1 - 8 1172

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          More Information


          Matching Taqman Gene Expression Assay:


          Hs00153340_m1

          Panther Classification:

          Molecular Function -

          P53-like transcription factor

          Gene Ontology Categories:

          Function(s) Process(es)

          negative regulation of transcription from RNA polymerase II promoter
          DNA strand renaturation
          base-excision repair
          nucleotide-excision repair
          regulation of transcription, DNA-templated
          transcription from RNA polymerase II promoter
          protein complex assembly
          cellular response to DNA damage stimulus
          DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
          DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
          ER overload response
          cell cycle arrest
          Ras protein signal transduction
          multicellular organism development
          cell aging
          protein localization
          cell proliferation
          negative regulation of cell proliferation
          determination of adult lifespan
          response to X-ray
          response to gamma radiation
          positive regulation of gene expression
          viral process
          protein sumoylation
          cell differentiation
          negative regulation of cell growth
          DNA damage response, signal transduction by p53 class mediator
          positive regulation of histone deacetylation
          chromatin assembly
          mitotic G1 DNA damage checkpoint
          positive regulation of protein oligomerization
          cellular response to UV
          cellular response to drug
          cellular response to glucose starvation
          intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
          regulation of apoptotic process
          positive regulation of apoptotic process
          negative regulation of apoptotic process
          entrainment of circadian clock by photoperiod
          proteasome-mediated ubiquitin-dependent protein catabolic process
          positive regulation of neuron apoptotic process
          negative regulation of transcription, DNA-templated
          positive regulation of transcription, DNA-templated
          positive regulation of transcription from RNA polymerase II promoter
          response to antibiotic
          positive regulation of protein export from nucleus
          regulation of mitochondrial membrane permeability
          negative regulation of fibroblast proliferation
          circadian behavior
          positive regulation of peptidyl-tyrosine phosphorylation
          negative regulation of helicase activity
          protein tetramerization
          negative regulation of telomerase activity
          positive regulation of thymocyte apoptotic process
          positive regulation of cell cycle arrest
          cellular response to hypoxia
          cellular response to ionizing radiation
          intrinsic apoptotic signaling pathway by p53 class mediator
          positive regulation of release of cytochrome c from mitochondria
          replicative senescence
          oxidative stress-induced premature senescence
          intrinsic apoptotic signaling pathway
          oligodendrocyte apoptotic process
          positive regulation of execution phase of apoptosis
          positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
          regulation of signal transduction by p53 class mediator
          regulation of cell cycle G2/M phase transition
          positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
          positive regulation of reactive oxygen species metabolic process
          positive regulation of intrinsic apoptotic signaling pathway
          RNA polymerase II transcription factor activity, sequence-specific DNA binding
          core promoter sequence-specific DNA binding
          RNA polymerase II transcription factor binding
          transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
          protease binding
          p53 binding
          DNA binding
          chromatin binding
          damaged DNA binding
          double-stranded DNA binding
          transcription factor activity, sequence-specific DNA binding
          copper ion binding
          protein binding
          ATP binding
          transcription factor binding
          zinc ion binding
          enzyme binding
          protein kinase binding
          protein phosphatase binding
          receptor tyrosine kinase binding
          ubiquitin protein ligase binding
          histone acetyltransferase binding
          identical protein binding
          sequence-specific DNA binding
          protein self-association
          transcription regulatory region DNA binding
          protein heterodimerization activity
          protein N-terminus binding
          chaperone binding
          protein phosphatase 2A binding

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