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See other EIF2AK3 SIRNA Assays ›
Gene Symbol:
Eif2ak3
Gene Name:
eukaryotic translation initiation factor 2 alpha kinase 3
Gene Aliases:
AI427929, Pek, Perk
Chromosome Location:
Chr.6: 70844484 - 70905240 on Build GRCm38
UniGene ID:
Mm.247167
Species:
Mouse
Species Specific ID (Flybase ID):
-
siRNA ID
158369
Purification
Standard
HPLC
In-Vivo Ready
Size
5 nmol
20 nmol
20 nmol
Cy3 | 20 nmol
FAM | 20 nmol
40 nmol
40 nmol
100 nmol
250 nmol
250 nmol
1 umol
10 umol
5 nmol
20 nmol
20 nmol
Cy3 | 20 nmol
FAM | 20 nmol
40 nmol
40 nmol
100 nmol
250 nmol
250 nmol
1 umol
10 umol
5 nmol
20 nmol
20 nmol
Cy3 | 20 nmol
FAM | 20 nmol
40 nmol
40 nmol
100 nmol
250 nmol
250 nmol
1 umol
10 umol
Availability
Inventoried
Catalog #
AM16708
Price
4,126.00
Your Price
Online offer:
4126.0
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Genomic Map
siRNA Details
More Information
Genomic Map
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siRNA Details
Gene Symbol: Eif2ak3
Interrogated Sequence
Translated Protein
Targeted Exon(s)
siRNA Location
IMAGE Clone ID
RefSeq
NM_010121.2
NP_034251.2
5
1021
GenBank mRNA
AF076681.1
-
5
1013
AK139679.1
-
3
343
BC054809.1
-
5
1033
6839221
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More Information
Other Species Targeted
This siRNA also targets the following transcripts in Rat: NM_031599, XM_006236624, XM_006236623, XM_008762977, AF096835.
Panther Classification:
Molecular Function -
non-receptor serine/threonine protein kinase
Gene Ontology Categories:
Function(s)
Process(es)
skeletal system development
ossification
angiogenesis
chondrocyte development
translation
regulation of translation
protein phosphorylation
activation of cysteine-type endopeptidase activity involved in apoptotic process
ER overload response
response to unfolded protein
endoplasmic reticulum organization
lactation
positive regulation of signal transduction
positive regulation of vascular endothelial growth factor production
positive regulation of gene expression
negative regulation of gene expression
regulation of translational initiation by eIF2 alpha phosphorylation
phosphorylation
negative regulation of translation
peptidyl-serine phosphorylation
regulation of fatty acid metabolic process
calcium-mediated signaling
bone mineralization
endoplasmic reticulum unfolded protein response
pancreas development
endocrine pancreas development
negative regulation of myelination
negative regulation of translation in response to stress
positive regulation of protein binding
SREBP signaling pathway
response to endoplasmic reticulum stress
PERK-mediated unfolded protein response
cellular response to glucose starvation
negative regulation of apoptotic process
fat cell differentiation
positive regulation of transcription from RNA polymerase I promoter
protein autophosphorylation
insulin-like growth factor receptor signaling pathway
protein homooligomerization
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
positive regulation of protein localization to nucleus
negative regulation of translation in response to endoplasmic reticulum stress
regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
positive regulation of glutathione biosynthetic process
positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
eukaryotic translation initiation factor 2alpha kinase activity
protein binding
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
enzyme binding
protein phosphatase binding
identical protein binding
Hsp90 protein binding
eukaryotic initiation factor eIF2 binding
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