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          System Message

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          LOADING ...
          See other TLR2 SIRNA Assays ›
          Gene Symbol:
          Tlr2
          Gene Name:
          toll-like receptor 2
          Gene Aliases:
          Ly105
          Chromosome Location:
          Chr.3: 83836272 - 83841825 on Build GRCm38
          UniGene ID:
          Mm.87596
          Species:
          Mouse
          Species Specific ID (Flybase ID):
          -
          siRNA ID 70425

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price 286.00
          Your Price
          Online offer: 277.65
          277.65
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: Tlr2
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_011905.3 NP_036035.3 3 435
          GenBank mRNA AF124741.1 - 3 374
          AF165189.1 - 3 399
          AF185284.1 - 3 389
          AF216289.1 - 3 398
          AK005043.1 - 3 436
          AK154504.1 - 3 405
          AY179346.1 - 2 250
          BC014693.1 - 3 594 3966249
          BY743020.1 - 3 403

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          More Information


          Gene Ontology Categories:

          Function(s) Process(es)

          microglial cell activation
          toll-like receptor signaling pathway
          response to molecule of bacterial origin
          response to molecule of fungal origin
          cytokine secretion involved in immune response
          immune system process
          positive regulation of leukocyte migration
          regulation of dendritic cell cytokine production
          cell surface pattern recognition receptor signaling pathway
          MyD88-dependent toll-like receptor signaling pathway
          leukotriene metabolic process
          inflammatory response
          immune response
          signal transduction
          I-kappaB phosphorylation
          negative regulation of cell proliferation
          response to bacterium
          positive regulation of Wnt signaling pathway
          central nervous system myelin formation
          response to bacterial lipoprotein
          response to peptidoglycan
          interleukin-10 production
          negative regulation of interleukin-12 production
          negative regulation of interleukin-17 production
          positive regulation of chemokine production
          positive regulation of interferon-beta production
          positive regulation of interleukin-10 production
          positive regulation of interleukin-12 production
          positive regulation of interleukin-18 production
          positive regulation of interleukin-6 production
          positive regulation of interleukin-8 production
          positive regulation of tumor necrosis factor production
          positive regulation of toll-like receptor signaling pathway
          toll-like receptor 2 signaling pathway
          positive regulation of NF-kappaB import into nucleus
          detection of triacyl bacterial lipopeptide
          detection of diacyl bacterial lipopeptide
          positive regulation of tumor necrosis factor biosynthetic process
          chloramphenicol transport
          negative regulation of growth of symbiont in host
          innate immune response
          positive regulation of nitric oxide biosynthetic process
          positive regulation of transcription from RNA polymerase II promoter
          nitric oxide metabolic process
          positive regulation of oligodendrocyte differentiation
          regulation of cytokine secretion
          positive regulation of cytokine secretion
          positive regulation of inflammatory response
          defense response to Gram-positive bacterium
          positive regulation of NF-kappaB transcription factor activity
          positive regulation of nitric-oxide synthase biosynthetic process
          induction by symbiont of defense-related host nitric oxide production
          positive regulation of macrophage cytokine production
          response to fatty acid
          cellular response to bacterial lipopeptide
          cellular response to lipoteichoic acid
          cellular response to peptidoglycan
          cellular response to diacyl bacterial lipopeptide
          cellular response to triacyl bacterial lipopeptide
          receptor activity
          transmembrane signaling receptor activity
          protein binding
          signaling pattern recognition receptor activity
          triacyl lipopeptide binding
          diacyl lipopeptide binding
          peptidoglycan binding
          protein heterodimerization activity
          lipoteichoic acid binding
          lipopeptide binding

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