Wall Pellitory
Allergy Facts, Symptoms, and Treatment


A bushy, wind-pollinated, perennial weed, wall pellitory is common in the Mediterranean and along the west coast of Europe. It's also been introduced in other parts of Europe and the Middle East as well as in North and South America and Australia. It prefers to root near surfaces such as rocks, banks, and walls, hence its name.1 Wall pellitory has two long flowering periods, so while its pollen appears at the beginning of spring, it persists throughout the spring and summer and into fall.2 The pollen from this severely allergenic plant causes symptoms of asthma, allergic conjunctivitis, and allergic rhinitis (hay fever).1,3 Wall pellitory is also known by names such as pellitory-of-the-wall, parietaire, spreading pellitory, asthma weed, and sticky-weed.1

Where is wall pellitory found?

Wall pellitory is common in the Mediterranean and along the west coast of Europe. It's also been introduced in other parts of Western Europe, Argentina, and Australia, and two related species are found in Brazil and the United States.1

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Are there other allergens I could be sensitized to?*

Many patients with wall pellitory allergy can experience symptoms when exposed to other allergens such as tree, weed, or grass pollens, making it difficult to determine which pollen is causing the symptoms, especially when pollen seasons are overlapping. This is called cross-reactivity and occurs when your body's immune system identifies the proteins, or components, in different substances as being structurally similar or biologically related, thus triggering a response.5 Other respiratory allergens that may cause reactions associated with wall pellitory are certain grasses, trees, and weeds (e.g., birch, alder, juniper, ragweed, olive, goosefoot, pigweed).6

Knowing the proteins, or components, within each allergen that are triggering your symptoms can help guide your management plan. With that in mind, and based on your symptom history, your healthcare provider may suggest something called a specific IgE component test, which can help reveal other pollens and foods you may react to. Results from this test can also help your healthcare provider decide if allergen immunotherapy may reduce your symptoms.5

Already have your specific IgE component test results?

Your component test results will include the name of the components (a series of letters and numbers). Your healthcare provider will likely review the results with you, but here you'll find an at-a-glance breakdown you can use as a reference. Simply match the component names to the list below to see what they mean in terms of symptom management.5

rPar j 2 

  • Indicates that symptoms may be caused by wall pellitory pollen.5
  • Wall pellitory pollen immunotherapy may be considered.5
  • May be associated with PFAS symptoms after ingestion of plant foods, e.g., vegetables, fruits, and nuts. Investigation of food allergy may be considered.5

rPhl p 7

  • Indicates symptoms may be caused by grass or by other pollen, e.g., from trees and weeds. Further investigation may be considered to confirm all allergy triggers.5
  • May be associated with more severe symptoms and higher prevalence of asthma than other grass pollen allergies.5

rPhl p 12

  • Indicates that symptoms may be caused by grass or by other pollen, e.g., from trees and weeds.

MUXF3 (CCD)

  • Positive specific IgE for wall pellitory in combination with MUXF3 CCD (Cross-Reactive Carbohydrate Determinant) being the only positive component test indicates that the cause of symptoms may be something other than wall pellitory pollen.5

Test results should be interpreted by your healthcare provider in the context of your clinical history. Final diagnosis and decision on further management is made by your healthcare provider.

*These products may not be approved for clinical use in your country. Please work with your healthcare provider to understand availability.

How do I manage my allergy?

The management of allergic rhinitis includes avoidance of relevant allergens, symptomatic treatment, and allergen immunotherapy.6-8

  • Check local pollen counts daily and limit time outside when pollen counts are high. Rain helps clear pollen from the air, so the best time to go outside is after a good rain.
  • Delegate outdoor chores whenever possible and wear a pollen mask if you must do outside tasks. 
  • Keep windows closed and use air conditioning instead.
  • Wash bedding at least once a week in hot, soapy water.
  • Wash your clothes after outdoor activities and dry all clothes in a dryer as opposed to line drying outdoors.
  • Bathe and wash your hair every day before bedtime to keep pollen out of your bed.
  • Wipe off any pets to remove pollen before letting them into your home.
  • Ensure everyone removes their shoes before entering your home.
  • Use certified asthma and allergy air filters.
  • Pharmacological treatment, including antihistamines, corticosteroids, decongestants, and saline douches.
  • Allergen immunotherapy as directed by your healthcare provider.

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Common Symptoms

Wall pellitory allergy symptoms can be similar to many other pollen allergies and may include:4,6

  • Sneezing
  • Nasal congestion
  • Runny nose
  • Watery eyes
  • Itchy throat and eyes
  • Wheezing

If you're sensitized to wall pellitory and have asthma, the weed pollen may trigger or worsen asthma symptoms, such as coughing and wheezing.4,6

How do I know if I'm allergic?*

Together with your symptom history, skin-prick testing or specific IgE blood testing can help determine if you are sensitized to a particular allergen. If you are diagnosed with an allergy, your healthcare provider will work with you to create a management plan.

*These products may not be approved for clinical use in your country. Please work with your healthcare provider to understand availability.

Pollen Season

Wall pellitory has two long flowering periods. So while its pollen appears at the beginning of spring, it persists throughout the spring and summer and into the fall.2 However, most patients sensitized to wall pellitory experience clinical symptoms prevalently in the spring.1

  1. Steinman H. Weed pollens. Allergy Resources International. 2009. Available from: http://www.immunocapexplorer.com/uploads/cms/asset_brick/asset/10415/52-5107-92_02-Weed_pollens.pdf.
  2. D'Amato, G., Cecchi, L., Bonini, S., Nunes, C., Annesi-Maesano, I., Behrendt, H., Liccardi, G., Popov, T. and Van Cauwenberge, P. (2007), Allergenic pollen and pollen allergy in Europe. Allergy, 62: 976-990. doi:10.1111/j.1398-9995.2007.01393.x.
  3. Pollen.com [Internet]. Plymouth Meeting, PA: IQVIA Inc.; 2020. Available from: https://www.pollen.com/research/genus/parietaria.
  4. American College of Allergy, Asthma & Immunology [Internet]. Arlington Heights, IL: American College of Allergy, Asthma & Immunology; 2014 [2018 Apr 23]. Available from: https://acaai.org/allergies/types/pollen-allergy.
  5. EAACI, et al. Molecular allergology user's guide. Pediatr Allergy Immunol. 2016 May;27 Suppl 23:1-250. doi: 10.1111/pai.12563. PMID: 27288833. Available from: http://www.eaaci.org/documents/Molecular_Allergology-web.pdf.
  6. Roberts, G., Xatzipsalti, M., Borrego, L., Custovic, A., Halken, S., Hellings, P., Papadopoulos, N., Rotiroti, G., Scadding, G., Timmermans, F., Valovirta, E. Paediatric rhinitis: Position paper of the European Academy of Allergy and Clinical Immunology. Allergy. 2013 Sep;68(9):1102-16.
  7. Asthma and Allergy Foundation of America [Internet]. Arlington, VA: Asthma and Allergy Foundation of America; 2019 Apr 9. Available from: https://community.aafa.org/blog/tips-for-preventing-allergic-reactions-to-tree-and-grass-pollen.
  8. Mayo Clinic [Internet]. Rochester, MN: Mayo Foundation for Medical Education and Research; 2020 Apr 16. Available from: https://www.mayoclinic.org/diseases-conditions/hay-fever/in-depth/seasonal-allergies/art-20048343.