MRAP encodes a melanocortin receptor-interacting protein. The encoded protein regulates trafficking and function of the melanocortin 2 receptor in the adrenal gland. The encoded protein can also modulate signaling of other melanocortin receptors. Mutations in this gene have been associated with familial glucocorticoid deficiency type 2.
B27; Fat cell-specific low molecular weight protein; Fat tissue-specific low MW protein; Melanocortin-2 receptor accessory protein
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