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Proteintech
TGFBI / BIGH3 Polyclonal Antibody
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FIGURE: 1 / 20
TGFBI / BIGH3 Antibody (10188-1-AP) in ICC/IF
Immunofluorescent analysis of (-20°C Methanol) fixed A549 cells, untreated (left) or TGF-beta-treated (right), using TGFBI/BIGH3 antibody (Product # 10188-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Product Details
10188-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TGFBI / BIGH3 Fusion Protein Ag0241 (199-406 aa encoded by BC000097)
Conjugate
Form
Liquid
Concentration
0.23 mg/mL
Amount
34.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: NIQIHHYPN GIVTVNCARL LKADHHATNG VVHLIDKVIS TITNNIQQII EIEDTFETLR AAVAASGLNT MLEGNGQYTL LAPTNEAFEK IPSETLNRIL GDPEALRDLL NNHILKSAMC AEAIVAGLSV ETLEGTTLEV GCSGDMLTIN GKAIISNKDI LATNGVIHYI DELLIPDSAK TLFELAAESD VSTAIDLFRQ AGLGNHLSG (199-406 aa encoded by BC000097)
Target Information
This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Beta ig-h3; beta-ig-h3; betaig-h3; Kerato-epithelin; RGD-CAP; RGD-containing collagen-associated protein; transforming growth factor beta-induced 68kDa; transforming growth factor, beta induced, 68 kDa; transforming growth factor, beta-induced, 68kD; Transforming growth factor-beta-induced protein ig-h3; unnamed protein product
Gene Aliases: 68kDa; AI181842; AI747162; Beta-ig; Big-h3; BIGH3; CDB1; CDG2; CDGG1; CSD; CSD1; CSD2; CSD3; EBMD; LCD1; TGFBI
UniProt ID: (Human) Q15582, (Mouse) P82198
Entrez Gene ID: (Human) 7045, (Mouse) 21810, (Rat) 116487
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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