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ABHD4 Polyclonal Antibody
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Product Details
BS-7948R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human ABHD4, amino acids 32-110.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
The α/β hydrolase superfamily is comprised of diverse members that are involved in important biochemical processes and related to various diseases. They have unrelated sequences, various substrates, and different kinds of catalytic activities, yet they share the same canonical α/β hydrolase fold, which consists of an eight-stranded parallel α/β structure. They are also characterized by a catalytic triad composed of a histidine, an acid and a nucleophile. Members of this superfamily are often drug targets for treating diseases, such as diabetes, Alzheimer's disease, obesity and blood clotting disorders. ABHD1 plays a role in metabolizing smoking xenobiotics. ABHD2 participates in the development of atherosclerosis. ABHD4 is involved in an alternative synthesis pathway of NAE. ABHD4 is a lysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE) which participates in the biosynthesis of N-acyl ethanolamines. Mutations in ABHD5 contribute to Chanarin-Dorfman syndrome. ABDH6 may play a role in nervous system metabolism and signaling. ABHD14A is possibly involved in granule neuron development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: (Lyso)-N-acylphosphatidylethanolamine lipase; Abhydrolase domain-containing protein 4; Alpha/beta hydrolase domain-containing protein 4; Alpha/beta-hydrolase 4; lyso-N-acylphosphatidylethanolamine lipase; protein ABHD4; unnamed protein product
Gene Aliases: 1110035H23Rik; ABH4; ABHD4; AI429574
UniProt ID: (Human) Q8TB40, (Mouse) Q8VD66
Entrez Gene ID: (Human) 63874, (Rat) 364380, (Mouse) 105501
lysophospholipase activity
protein binding
hydrolase activity
lysophosphatidic acid acyltransferase activity
phospholipase activity
prenylcysteine methylesterase activity
lipase activity
1-oxa-2-oxocycloheptane lactonase activity
sulfolactone hydrolase activity
3,4-dihydrocoumarin hydrolase activity
butyrolactone hydrolase activity
endosulfan lactone lactonase activity
L-ascorbate 6-phosphate lactonase activity
Ser-tRNA(Thr) hydrolase activity
Ala-tRNA(Pro) hydrolase activity
Cys-tRNA(Pro) hydrolase activity
Ser(Gly)-tRNA(Ala) hydrolase activity
all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity
retinyl-palmitate esterase activity
mannosyl-oligosaccharide 1,6-alpha-mannosidase activity
mannosyl-oligosaccharide 1,3-alpha-mannosidase activity
methyl indole-3-acetate esterase activity
methyl salicylate esterase activity
methyl jasmonate esterase activity
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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