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Bioss
APOH Polyclonal Antibody
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FIGURE: 1 / 3
APOH Antibody (BS-1570R) in IHC (P)
Formalin-fixed and paraffin embedded human laryngeal cancer tissue labeled with Anti-APOH Polyclonal Antibody, Unconjugated (bs-1570R) at 1:200 followed by conjugation to the secondary antibody, Goat Anti-Rabbit IgG, AF488 conjugated (bs-0295G-AF488), and DAPI staining.
Product Details
BS-1570R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human ApoH, amino acids 281-345.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Apolipoprotein H has been implicated in a variety of physiologic pathways including lipoprotein metabolism, coagulation, and the production of antiphospholipid autoantibodies. APOH may be a required cofactor for anionic phospholipid binding by the antiphospholipid autoantibodies found in sera of many patients with lupus and primary antiphospholipid syndrome, but it does not seem to be required for the reactivity of antiphospholipid autoantibodies associated with infections.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 2GPI; Activated protein C-binding protein; Anticardiolipin cofactor; APC inhibitor; Apo-H; Apolipoprotein H; apolipoprotein H (beta-2-glycoprotein I); B2GPI; beta(2)GPI; Beta-2-glycoprotein 1; Beta-2-glycoprotein I
Gene Aliases: APOH; B2G1; B2GP1; B2GPI; beta-2-GPI; beta2-GPI; BG
UniProt ID: (Human) P02749, (Mouse) Q01339
Entrez Gene ID: (Human) 350, (Rat) 287774, (Mouse) 11818
negative regulation of endothelial cell proliferation
triglyceride metabolic process
blood coagulation
blood coagulation, intrinsic pathway
negative regulation of endothelial cell migration
negative regulation of angiogenesis
regulation of blood coagulation
negative regulation of blood coagulation
organ regeneration
plasminogen activation
negative regulation of myeloid cell apoptotic process
triglyceride transport
negative regulation of smooth muscle cell apoptotic process
positive regulation of lipoprotein lipase activity
regulation of fibrinolysis
negative regulation of fibrinolysis
platelet degranulation
aging
positive regulation of triglyceride catabolic process
positive regulation of blood coagulation
response to triglyceride
negative regulation of respiratory burst
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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