Immunogen sequence: MVADPPRDSK GLAAAEPTAN GGLALASIED QGAAAGGYCG SRDQVRRCLR ANLLVLLTVV AVVAGVALGL GVSGAGGALA LGPERLSAFV FPGELLLRLL; Positive Samples: Rat lung; Cellular Location: Cell membrane, Melanosome, Multi-pass membrane protein
SLC1A5 (Solute carrier family 1 (neutral amino acid transporter), member 5) is a member of the Na(+)-dependent amino acid transporter superfamily. It has a broad substrate specificity, a preference for zwitterionic amino acids, and a sodium-dependence. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated amino acids, anionic amino acids, and cationic amino acids. It acts as a cell surface receptor for feline endogenous virus RD114, baboon M7 endogenous virus and type D simian retroviruses.
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Protein Aliases: ATB0; CAZ-associated structural protein; H4-system ASC-like transporter; neutral amino acid transporter B(0); sodium-dependent neutral amino acid transporter ASCT2; solute carrier family 1, member 7
Gene Aliases: Asct2; H4-ASCT2; Slc1a7
Entrez Gene ID: (Rat) 292657