|Tested species reactivity||Human, Mouse|
|Published species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 92-118 amino acids from the central region of human BTG1|
|Purification||Antigen affinity chromatography|
|Contains||0.09% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry (Frozen) (IHC (F))||See 1 publications below|
This antibody is predicted to react with bovine, chicken and rat based on sequence homology.
BTG1 is a member of an anti-proliferative gene family that regulates cell growth and differentiation. Expression of this gene is highest in the G0/G1 phases of the cell cycle and downregulated when cells progressed through G1. The encoded protein interacts with several nuclear receptors, and functions as a coactivator of cell differentiation. This locus has been shown to be involved in a t(8;12)(q24;q22) chromosomal translocation in a case of B-cell chronic lymphocytic leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
B¿cell translocation gene 1 serves as a novel prognostic indicator of hepatocellular carcinoma.
PA5-25035 was used in immunohistochemistry - frozen section to evaluate the prognostic value of B-cell translocation gene 1 in hepatocellular carcinoma
|Kanda M,Sugimoto H,Nomoto S,Oya H,Hibino S,Shimizu D,Takami H,Hashimoto R,Okamura Y,Yamada S,Fujii T,Nakayama G,Koike M,Fujiwara M,Kodera Y||International journal of oncology (46:641)||2015|