Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK. Does not show detyrosinase or deglycylase activities from the carboxy-terminus of tubulin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ATP/GTP binding protein-like 2; ATP/GTP-binding protein-like 2; CBCP2; cytoplasmic carboxypeptidase 2; Cytosolic carboxypeptidase 2; Protein deglutamylase CCP2; testis tissue sperm-binding protein Li 96mP
Gene Aliases: AGBL2; CCP2
UniProt ID: (Human) Q5U5Z8
Entrez Gene ID: (Human) 79841
Molecular Function: metalloprotease