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          • Primary Antibodies ›
          • CD3d Antibodies

          Invitrogen

          CD3d Polyclonal Antibody

          1 Reference
          View all (16) CD3d antibodies

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          Cite CD3d Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (1)
          CD3d Antibody in Western Blot (WB)
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          CD3d Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          CD3d Antibody (PA5-28313) in WB

          Western Blot using CD3d Polyclonal Antibody (Product # PA5-28313). Sample (30 µg of whole cell lysate). Lane A: Jurkat membrane. 12% SDS PAGE. CD3d Polyclonal Antibody (Product # PA5-28313) diluted at 1:10,000. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
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          View Product

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          CD3d Antibody in Western Blot (WB)

          Product Details

          PA5-28313

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:5,000-1:20,000
          -

          Immunohistochemistry (IHC)

          -
          View 1 publication 1 publication
          Product Specifications

          Species Reactivity

          Human

          Published species

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein encompassing a sequence within the center region of human CD3 delta. The exact sequence is proprietary.

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Amount

          100 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7, with 20% glycerol

          Contains

          0.01% thimerosal

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2545789

          Product Specific Information

          Recommended positive controls: Jurkat membrane.

          Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

          Target Information

          CD3d is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The CD3d protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in the CD3d gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms of CD3d have been found. Other variants of CD3d may also exist, but the full-length nature of their transcripts have yet to be defined.

          ⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: CD3 antigen, delta subunit; CD3 delta; CD3d; CD3d antigen, delta polypeptide (TiT3 complex); CD3d molecule, delta (CD3-TCR complex); OKT3, delta chain; T-cell receptor T3 delta chain; T-cell surface glycoprotein CD3 delta chain; unnamed protein product

          View more View less

          Gene Aliases: CD3-DELTA; CD3D; CD3DELTA; IMD19; T3D

          View more View less

          UniProt ID: (Human) P04234

          View more View less

          Entrez Gene ID: (Human) 915

          View more View less

          Function(s)
          transmembrane signaling receptor activity protein binding identical protein binding
          Process(es)
          adaptive immune response immune system process cell surface receptor signaling pathway positive thymic T cell selection alpha-beta T cell activation T cell receptor signaling pathway
          It has to be done as per old AB suggested Products section.

          Disclaimer

          Close

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

          Learn more
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          We're here to help

          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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