In IHC applications, antigen retrieval using a citrate buffer (pH 6.0) is recommended.
PA5-32889 has successfully been used to detect CD61 in IHC in human and mare placenta.
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%) Marmoset (93%) Dog, Panda (86%).
The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling.
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Protein Aliases: antigen CD61; BDPLT2; CD61; GP3A; GPIIIa; integrin beta 3; Integrin beta-3; integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61); ITGB3; platelet glycoprotein IIIa; platelet glycoprotein IIIa integrin subunit beta 3; Platelet membrane glycoprotein IIIa
Gene Aliases: BDPLT16; BDPLT2; CD61; GP3A; GPIIIa; GT; ITGB3
UniProt ID: (Human) P05106