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OriGene
SULT1A1 Monoclonal Antibody (OTI8B8), TrueMAB™
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Product Details
CF501820
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
OTI8B8
Immunogen
Full length human recombinant protein of human SULT1A1 produced in HEK293T cell.
Conjugate
Form
Lyophilized
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 8% trehalose
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
Target Information
The soluble sulfotransferases contribute to the elimination of xenobiotics, the activation of procarcinogens and the regulation of hormones by catalyzing the sulfate conjugation of these substances. Members of the three groups comprising this superfamily (namely SULT1, SULT2 and SULT3) show selectivity to certain substrate compounds. SULT1A1 (sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1), also known as STP or STP1, is a 295 amino acid protein that localizes to the cytoplasm and belongs to the sulfotransferase family. Functioning as a homodimer that is expressed in brain, liver, skin and lung tissue, SULT1A1 catalyzes the sulfate conjugation of catecholamines, phenolic drugs and neurotransmitters and, via this catalytic activity, plays a role in the elimination of a variety of compounds from the body. Additionally, SULT1A1 may be involved in the activation of carcinogenic N-hydroxyarylamines, indicating a possible role in carcinogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Aryl sulfotransferase 1; CSPS; HAST1/HAST2; MGC131921; MGC5163; OTTHUMP00000162568; OTTHUMP00000162569; P PST; P PST 1; P-PST 1; Phenol sulfotransferase 1; Phenol-sulfating phenol sulfotransferase 1; ST1A1; ST1A3; Sulfotransferase 1A1; sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1; Thermostable phenol sulfotransferase; thermostable phenol sulfotransferase1; Ts-PST
Gene Aliases: HAST1/HAST2; OK/SW-cl.88; P-PST; P-PST 1; PST; ST1A1; ST1A3; STP; STP1; SULT1A1; ts-PST; TSPST1
UniProt ID: (Human) P50225
Entrez Gene ID: (Human) 6817
ethanol catabolic process
catecholamine metabolic process
lipid metabolic process
xenobiotic metabolic process
steroid metabolic process
estrogen metabolic process
amine metabolic process
flavonoid metabolic process
thyroid hormone metabolic process
dopamine catabolic process
3'-phosphoadenosine 5'-phosphosulfate metabolic process
sulfation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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