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Proteintech
AIM2 Monoclonal Antibody (3E12A8), CoraLite® Plus 488
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Product Details
CL488-66902
Product Specifications
Species Reactivity
Human,
Mouse,
Rabbit,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
3E12A8
Immunogen
AIM2 fusion protein Ag14607
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 0.5% BSA, 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: MESKYKEIL LLTGLDNITD EELDRFKFFL SDEFNIATGK LHTANRIQVA TLMIQNAGAV SAVMKTIRIF QKLNYMLLAK RLQEEKEKVD KQYKSVTKPK PLSQAEMSPA ASAAIRNDVA KQRAAPKVSP HVKPEQKQMV AQQESIREGF QKRCLPVMVL KAKKPFTFET QEGKQEMFHA TVATEKEFFF VKVFNTLLKD KFIPKRIIII ARYYRHSGFL EVNSASRVLD AESDQKVNVP LNIIRKAGET PKINTLQTQP LGTIVNGLFV VQKVTEKKKN ILFDLSDNTG KMEVLGVRNE DTMKCKEGDK VRLTFFTLSK NGEKLQLTSG VHSTIKVIKA KKKK
Target Information
AIM2 is a member of the IFI20X /IFI16 family. It plays a putative role in tumorigenic reversion and may control cell proliferation. Interferon-gamma induces expression of AIM2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Absent in melanoma 2; Ifi-210; Interferon-inducible protein 210; Interferon-inducible protein AIM2; Interferon-inducible protein p210; RP11-520H16.3; unnamed protein product
Gene Aliases: AIM2; Gm1313; Ifi210; PYHIN4
UniProt ID: (Human) O14862, (Mouse) Q91VJ1
Entrez Gene ID: (Human) 9447, (Rat) 304987, (Mouse) 383619
activation of innate immune response
pattern recognition receptor signaling pathway
positive regulation of defense response to virus by host
immune system process
inflammatory response
immune response
cellular response to DNA damage stimulus
brain development
negative regulation of NF-kappaB transcription factor activity
positive regulation of interleukin-1 beta production
tumor necrosis factor-mediated signaling pathway
cellular response to interferon-beta
T cell homeostasis
innate immune response
positive regulation of inflammatory response
regulation of behavior
positive regulation of NF-kappaB transcription factor activity
protein maturation
defense response to virus
negative regulation of protein kinase B signaling
neuron cellular homeostasis
pyroptosis
cellular response to cytokine stimulus
cellular response to xenobiotic stimulus
AIM2 inflammasome complex assembly
pyroptotic cell death
pyroptosome complex assembly
biological_process
positive regulation of protein oligomerization
cellular response to drug
interleukin-1 beta secretion
positive regulation of interleukin-1 beta secretion
positive regulation of cysteine-type endopeptidase activity
apoptotic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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