Search
Proteintech
DPEP1 Monoclonal Antibody (2B4F4), CoraLite® Plus 488
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
CL488-68081
Product Specifications
Species Reactivity
Human,
Mouse,
Pig,
Rat
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
2B4F4
Immunogen
Recombinant protein
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Purification
Protein A
Storage buffer
PBS with 50% glycerol, 0.5% BSA
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: MWSGWWLWPL VAVCTADFFR DEAERIMRDS PVIDGHNDLP WQLLDMFNNR LQDERANLTT LAGTHTNIPK LRAGFVGGQF WSVYTPCDTQ NKDAVRRTLE QMDVVHRMCR MYPETFLYVT SSAGIRQAFR EGKVASLIGV EGGHSIDSSL GVLRALYQLG MRYLTLTHSC NTPWADNWLV DTGDSEPQSQ GLSPFGQRVV KELNRLGVLI DLAHVSVATM KATLQLSRAP VIFSHSSAYS VCASRRNVPD DVLRLVKQTD SLVMVNFYNN YISCTNKANL SQVADHLDHI KEVAGARAVG FGGDFDGVPR VPEGLEDVSK YPDLIAELLR RNWTEAEVKG ALADNLLRVF EAVEQASNLT QAPEEEPIPL DQLGGSCRTH YGYSS
Target Information
The protein encoded by this gene is a kidney membrane enzyme involved in the metabolism of glutathione and other similar proteins by dipeptide hydrolysis. The encoded protein is known to regulate leukotriene activity by catalyzing the conversion of leukotriene D4 to leukotriene E4. This protein uses zinc as a cofactor and acts as a disulfide-linked homodimer. Two transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: Beta-lactamase; Dehydropeptidase-I; Dipeptidase 1; dipeptidase 1 (renal); DPEP-1; DPEP1; hRDP; MBD-1; membrane bound dipeptidase type II; Membrane-bound dipeptidase 1; Microsomal dipeptidase; Renal dipeptidase; testicular tissue protein Li 57
Gene Aliases: AI327012; DPEP1; MBD; MBD1; MDP; RDP
UniProt ID: (Human) P16444, (Pig) P22412, (Rat) P31430, (Mouse) P31428
Entrez Gene ID: (Human) 1800, (Pig) 397196, (Rat) 94199, (Mouse) 13479
protein binding
peptidase activity
metalloexopeptidase activity
metallopeptidase activity
zinc ion binding
beta-lactamase activity
hydrolase activity
dipeptidase activity
GPI anchor binding
metal ion binding
metallodipeptidase activity
modified amino acid binding
identical protein binding
cysteine-type endopeptidase inhibitor activity involved in apoptotic process
dipeptidyl-peptidase activity
protease
proteolysis
lipid metabolic process
leukotriene metabolic process
glutathione metabolic process
glutathione catabolic process
inflammatory response
antibiotic metabolic process
negative regulation of cell migration
neutrophil chemotaxis
homocysteine metabolic process
cellular response to calcium ion
cellular response to nitric oxide
cellular lactam catabolic process
leukotriene D4 catabolic process
GPI anchor release
apoptotic process
cellular response to insulin stimulus
cellular response to drug
negative regulation of apoptotic process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support