Search
Proteintech
DCT Monoclonal Antibody (1B3D4), CoraLite® Plus 488
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
CL488-68114
Product Specifications
Species Reactivity
Human,
Mouse,
Pig
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
1B3D4
Immunogen
DCT fusion protein Ag26165
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.5% BSA
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: MSPLWWGFL LSCLGCKILP GAQGQFPRVC MTVDSLVNKE CCPRLGAESA NVCGSQQGRG QCTEVRADTR PWSGPYILRN QDDRELWPRK FFHRTCKCTG NFAGYNCGDC KFGWTGPNCE RKKPPVIRQN IHSLSPQERE QFLGALDLAK KRVHPDYVIT TQHWLGLLGP NGTQPQFANC SVYDFFVWLH YYSVRDTLLG PGRPYRAIDF SHQGPAFVTW HRYHLLCLER DLQRLIGNES FALPYWNFAT GRNECDVCTD QLFGAARPDD PTLISRNSRF SSWETVCDSL DDYNHLVTLC NGTYEGLLRR NQMGRNSMKL PTLKDIRDCL SLQKFDNPPF FQNSTFSFRN A
Target Information
The TYR-related proteins, TRP1 and TRP2, are also specifically expressed in melanocytes, and they likewise contribute to the synthesis of melanin within the melanosomes. The TRPs, including TYR, all share a similar transmembrane region, contain two metal-binding regions and a cysteinerich epidermal growth factor motif, and are localized in the melanosomal membrane. These proteins, however, have distinct catalytic activity, and they individually contribute to the biosynthesis of melanin biopolymers. The TRPs are believed to exist as a multi-enzyme complex, as these proteins form aggregates together, and the expression of TRP1 also helps stabilize TYR in melanocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: DCT; DOPAchrome conversion factor; dopachrome delta-isomerase; DOPAchrome isomerase; DOPAchrome oxidoreductase; dopachrome tautomerase; dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2); dorpachrome tautomerase; DT; L-dopachrome Delta-isomerase; L-dopachrome isomerase; L-dopachrome tautomerase; SLATY locus protein; TRP-2; TRP2; tyrosinase related protein-2; Tyrosinase-related protein 2; tyrosinase-related protein-2; tyrosine-related protein 2; unnamed protein product
Gene Aliases: DCT; DT; OCA8; slaty; slt; TRP-2; TRP2; Tyrp-2; TYRP2
UniProt ID: (Pig) Q4R1H1, (Human) P40126, (Mouse) P29812
Entrez Gene ID: (Pig) 574066, (Human) 1638, (Mouse) 13190
melanin biosynthetic process from tyrosine
cell development
oxidation-reduction process
positive regulation of neuroblast proliferation
neuroblast proliferation
epidermis development
response to blue light
ventricular zone neuroblast division
melanin biosynthetic process
pigmentation
developmental pigmentation
metabolic process
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support