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Proteintech
ATP5J2 Monoclonal Antibody (2B3C3), CoraLite® Plus 488
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Product Details
CL488-68128
Product Specifications
Species Reactivity
Human,
Mouse,
Rabbit,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
2B3C3
Immunogen
ATP5J2 fusion protein Ag8811
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.5% BSA
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: MASVGECPA PVPVKDKKLL EVKLLELPSW ILMRDFSPSG IFGAFQRGYY RYYNKYINVK KGSISGITMV LACYVLFSYS FSYKHLKHER LRKYH
Target Information
The ATP5MF gene encodes the ATP synthase membrane subunit F, which is a part of the mitochondrial ATP synthase complex (Complex V). This complex plays a crucial role in the process of oxidative phosphorylation, where ADP is converted to ATP, the primary energy currency of the cell. The ATP synthase complex consists of two main domains: the F1 catalytic core and the F0 proton channel. ATP5MF is a component of the F0 domain, helping to form the membrane channel that facilitates proton translocation across the mitochondrial membrane. This proton translocation is essential for driving the synthesis of ATP. Mutations or dysfunction in the ATP5MF gene can lead to mitochondrial disorders, which can have significant implications for cellular energy production and are associated with various metabolic and neurodegenerative diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ATP synthase f chain, mitochondrial; ATP synthase F(0) complex subunit f, mitochondrial; ATP synthase membrane subunit f; ATP synthase subunit f, mitochondrial; ATP synthase, H+ transporting, mitochondrial F0 complex, subunit f; ATP synthase, H+ transporting, mitochondrial F0 complex, subunit f, isoform 2; ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F2; ATP synthase, H+ transporting, mitochondrial Fo complex subunit F2; ATP5J2; F1F0-type ATPase subunit f; F1Fo-ATP synthase complex Fo membrane domain f subunit; F1Fo-ATPase synthase f subunit; hypothetical protein, clone:2-31
Gene Aliases: 1110019H14Rik; ATP5J2; ATP5JL; ATP5MF
UniProt ID: (Human) P56134, (Rat) D3ZAF6, (Mouse) P56135
Entrez Gene ID: (Human) 9551, (Rat) 690441, (Mouse) 57423
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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