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Catalase Monoclonal Antibody (1F8D7), CoraLite® 594
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FIGURE: 1 / 2
Catalase Antibody (CL594-66765) in Flow
1X10^6 HepG2 cells were intracellularly stained with 0.8 µg CoraLite®594 Anti-Human Catalase (CL594-66765, Clone:1F8D7) (red), or 0.8 µg Control Antibody. Cells were fixed with 4% PFA and permeabilized with Intracellular Staining Permeabilization Wash Buffer.
Product Details
CL594-66765
Product Specifications
Species Reactivity
Human,
Mouse,
Pig,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
1F8D7
Immunogen
Recombinant protein
Conjugate
Excitation/Emission Max
593/614 nm
Form
Liquid
Purification
Protein G
Storage buffer
PBS with 50% glycerol, 0.5% BSA
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: EAVYCKFHYK TDQGIKNLSV EDAARLSQED PDYGIRDLFN AIATGKYPSW TFYIQVMTFN QAETFPFNPF DLTKVWPHKD YPLIPVGKLV LNRNPVNYFA EVEQIAFDPS NMPPGIEASP DKMLQGRLFA YPDTHRHRLG PNYLHIPVNC PYRARVANYQ RDGPMCMQDN QGGAPNYYPN SFGAPEQQPS ALEHSIQYSG EVRRFNTAND DNVTQVRAFY VNVLNEEQRK RLCENIAGHL KDAQIFIQKK AVKNFTEVHP DYGSHIQALL DKYNAEKPKN AIHTFVQSGS HLAAREKANL
Target Information
Catalase is a homotetrameric heme-containing enzyme present within the matrix of all peroxisomes. It carries out a dismutation reaction in which hydrogen peroxide is converted to water and oxygen. Human catalase has the last four amino acids (-KANL) at the extreme C-terminus for peroxisome targeting. The monomer of human catalase is 61.3 kDa in molecular size. Catalase has been implicated as an important factor in inflammation, mutagenesis, prevention of apoptosis, and stimulation of a wide spectrum of tumors. Loss of catalase leads to the human genetic disease, acatalasemia, or Takahara's disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CAT; Catalase; catalase 1; CTA1; epididymis secretory sperm binding protein; HGNC:1516; MGC138422; MGC138424; unnamed protein product
Gene Aliases: 2210418N07; Cas-1; Cas1; CAT; Cat01; Catl; Cs-1; CS1
UniProt ID: (Human) P04040, (Pig) O62839, (Rat) P04762, (Mouse) P24270
Entrez Gene ID: (Human) 847, (Pig) 397568, (Rat) 24248, (Mouse) 12359
aminoacylase activity
catalase activity
peroxidase activity
antioxidant activity
oxidoreductase activity
oxidoreductase activity, acting on peroxide as acceptor
enzyme binding
heme binding
identical protein binding
protein homodimerization activity
metal ion binding
NADP binding
receptor binding
peroxidase
response to reactive oxygen species
osteoblast differentiation
ureteric bud development
response to hypoxia
kidney development
triglyceride metabolic process
response to oxidative stress
cholesterol metabolic process
aerobic respiration
response to xenobiotic stimulus
response to UV
response to toxic substance
response to light intensity
UV protection
response to ozone
response to lead ion
response to activity
response to inactivity
hemoglobin metabolic process
response to estradiol
response to insulin
response to vitamin A
response to vitamin E
response to L-ascorbic acid
response to hydrogen peroxide
hydrogen peroxide catabolic process
negative regulation of apoptotic process
response to ethanol
response to cadmium ion
positive regulation of cell division
positive regulation of protein kinase B signaling
response to hyperoxia
cellular detoxification of hydrogen peroxide
response to fatty acid
cellular response to growth factor stimulus
response to amitrole
response to phenylpropanoid
oxidation-reduction process
cellular oxidant detoxification
aging
response to radiation
positive regulation of phosphatidylinositol 3-kinase signaling
negative regulation of NF-kappaB transcription factor activity
response to drug
positive regulation of NF-kappaB transcription factor activity
protein tetramerization
protein homotetramerization
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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