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Invitrogen
Cdc5L Polyclonal Antibody
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Product Details
PA5-52823
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human Cdc5L. Recombinant protein control fragment (Product #RP-102482).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: GAEGLTPRSG TTPKPVINST PGRTPLRDKL NINPEDGMAD YSDPSYVKQM ERESREHLRL GLLGLPAPKN DFEIVLPENA EKELEEREID DTYIEDAADV DARKQAIRDA ERVKEMKRMH KAVQKDLPRP SEVNETILR
Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 98%.
Target Information
The protein encoded by this gene shares a significant similarity with Schizosaccharomyces pombe cdc5 gene product, which is a cell cycle regulator important for G2/M transition. This protein has been demonstrated to act as a positive regulator of cell cycle G2/M progression. It was also found to be an essential component of a non-snRNA spliceosome, which contains at least five additional protein factors and is required for the second catalytic step of pre-mRNA splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CDC5 cell division cycle 5-like; Cdc5-like protein; Cdc5-related protein; Cell division cycle 5-like protein; dJ319D22.1 (CDC5-like protein); hCDC5; Pombe cdc5-related protein
Gene Aliases: CDC5; CDC5-LIKE; CDC5L; CEF1; dJ319D22.1; KIAA0432; PCDC5RP
UniProt ID: (Human) Q99459
Entrez Gene ID: (Human) 988
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II transcription factor recruiting
transcription corepressor binding
DNA binding
protein binding
protein phosphatase 1 binding
protein kinase binding
leucine zipper domain binding
sequence-specific DNA binding
transcription regulatory region DNA binding
poly(A) RNA binding
WD40-repeat domain binding
mitotic cell cycle
mRNA splicing, via spliceosome
DNA repair
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
cell differentiation
cellular response to fibroblast growth factor stimulus
cellular response to interleukin-2
signal transduction involved in DNA damage checkpoint
cellular response to wortmannin
cellular response to nerve growth factor stimulus
cellular response to prolactin
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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